Respiratory drive and ventilator care in acute respiratory failure

Who could benefit from this research

What this research studies

If you are an adult with severe lung failure needing a breathing machine, this project looks at how your own breathing effort changes the stress on your lungs during ventilation. The researchers will review how different ventilator settings and patient effort interact to cause either more or less lung injury, with a focus on the pattern and intensity of breathing drive. They will combine clinical data, imaging, and possibly physiological measurements to understand when spontaneous breathing helps or hurts the injured lung. The goal is to identify ways to titrate ventilation to minimize injury while supporting breathing. This work could guide more personalized ventilator strategies for patients with ARDS and related conditions.

Why it matters

Where this research is happening

• New York University School of Medicine
  New York, United States Active

Researchers

• Principal investigator: Beitler, Jeremy R. — New York University School of Medicine
• Study coordinator: Beitler, Jeremy R.

Related research

Other NIH-funded projects on the same topics.

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• Using a simple breathing test to check how kids recover lung function after severe lung illness

  A study will test a quick, noninvasive breathing test called oscillometry to see how well children who survived dangerous lung problems recover over time.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11324603

• Breathing effort and ventilator safety in severe respiratory failure

  This research looks at how a person's own breathing effort affects lung and diaphragm injury for adults on ventilators for acute respiratory failure.

  NIH research New York University School of Medicine · New York, United States · NIH-11258593

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.