Peer-led PrEP delivery for youth in Brazil: a trial to boost PrEP uptake
Official title: Determining the impact of peer-led, community-based PrEP delivery among youth in Brazil: A randomized controlled trial
Funded at University of Alabama at Birmingham · NIH-11403961 · Data updated 2026-11-12
A youth-focused program tests whether trained young peers delivering PrEP in community settings can help more teens in Brazil start and stay on PrEP.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | July 19, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $104,921 |
| NIH project number | 5R01MH135769-03 |
| Project ID | NIH-11403961 on NIH RePORTER |
Who could benefit from this research
✓Could help
Youth aged 13-24 in Brazil who are at risk for HIV and eligible for PrEP.
✕Less likely to help
Youth outside the target age range or without HIV risk factors may not benefit from this specific delivery model.
What this research studies
This project will test a model where trained youth peers are part of healthcare teams to deliver PrEP outside traditional clinics in Brazil. It uses a randomized design to compare the peer-led community delivery approach with standard care. If successful, it could show a practical way to reach more youth with PrEP and reduce new HIV infections among adolescents. The study builds on prior work with adolescent PrEP and peer navigation to address stigma, access, and logistical barriers. Outcomes will include PrEP uptake, adherence, and user experiences.
Why it matters
Potential benefit: If successful, the approach could substantially increase PrEP use among youth and help prevent new HIV infections.
How similar studies have gone: Prior adolescent PrEP work showed peer navigation can support engagement, suggesting potential for this approach to work in community settings.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Bruxvoort, Katia — University of Alabama at Birmingham
- Study coordinator: Bruxvoort, Katia
Related research
Other NIH-funded projects on the same topics.
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A brief alcohol support for PrEP users to boost HIV prevention
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Peer-led PrEP delivery for youth in Brazil: a community-based randomized trial
A youth-focused, community-based program tests whether trained young peers can help more adolescents get HIV PrEP in Brazil.
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Peer-led PrEP delivery for youth in Brazil: a youth-focused PrEP access trial
This project tests whether trained youth peer workers can deliver PrEP in community settings to increase PrEP uptake among young people in Brazil.
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Helping people on PrEP reduce drinking and stay on HIV prevention
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W-PrEP: clinic-level steps to help women get PrEP for HIV prevention
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.