Medications for opioid use disorder in older adults with multiple health issues
Official title: Use and effectiveness of medications for opioid use disorder in older adults with multimorbidity
Funded at University of Pittsburgh at Pittsburgh · NIH-11447399 · Data updated 2026-11-12
This project looks at how older adults living with opioid use disorder and multiple chronic conditions respond to medications for opioid use disorder.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | September 1, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $701,569 |
| NIH project number | 1R01DA064664-01A1 |
| Project ID | NIH-11447399 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 65 and older who have or are at risk for opioid use disorder and have multiple chronic health conditions.
✕Less likely to help
Patients without opioid use disorder or without multimorbidity may not directly benefit from this research.
What this research studies
Older adults with opioid use disorder often have several chronic conditions that complicate treatment. This study will gather and analyze data to understand which medications for opioid use disorder work best and are safest for people aged 65 and older with multimorbidity. Researchers will examine how age, comorbidities, and polypharmacy influence treatment choices, safety risks, and retention in care. The goal is to inform clinician-patient discussions and guide personalized treatment decisions for this growing population.
Why it matters
Potential benefit: If successful, the findings could help clinicians choose safer, more effective MOUD options for older adults with multiple health issues.
How similar studies have gone: Previous studies have shown variable safety and effectiveness of MOUD in older adults, with a need for clearer guidance in multimorbidity scenarios.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Park, Tae Woo — University of Pittsburgh at Pittsburgh
- Study coordinator: Park, Tae Woo
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Scaling up medications for opioid use disorder in residential treatment programs
This grant studies how to help residential treatment programs provide medications for opioid use disorder to reduce overdoses after discharge, focusing on real-world settings and policies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.