Investigating pain and medication interactions in older adults at risk for opioid issues
Official title: Pain, Multimorbidity, Opioid-Drug Interactions and Risk for Opioid Use Disorder or Overdose in Older Adults
Funded at Ohio State University · NIH-11012319 · Data updated 2026-11-12
This study is looking at how older adults with ongoing pain and other health issues might be at risk for problems with opioid use, and it aims to find ways to keep them safe while managing their pain.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | April 10, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $194,958 |
| NIH project number | 5R01HS029001-03 |
| Project ID | NIH-11012319 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing uncontrolled pain and taking multiple medications for chronic conditions.
✕Less likely to help
Patients who are not taking opioids or do not have chronic pain conditions may not benefit from this research.
What this research studies
This research focuses on older adults to explore how uncontrolled pain, multiple chronic conditions, and interactions between opioids and other medications may increase the risk of opioid use disorder or overdose. By conducting longitudinal assessments, the study aims to identify critical factors that contribute to these risks, especially as older adults face unique challenges with pain management and medication use. The findings could help develop targeted interventions to improve safety and treatment outcomes for this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies and reduced risk of opioid misuse among older adults.
How similar studies have gone: While there is ongoing research into opioid use and older adults, this specific focus on multimorbidity and drug interactions is relatively novel and has not been extensively studied.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Wei, Yu-Jung “jenny” — Ohio State University
- Study coordinator: Wei, Yu-Jung “jenny”
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.