Liver Cirrhosis Network: Coordinating Data for Better Care
Official title: Liver Cirrhosis Network: Scientific and Data Coordination Center
Funded at Northwestern University · NIH-11591404 · Data updated 2026-11-12
A national effort is coordinating data to improve care for people with advanced liver disease and its complications.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | August 28, 2021 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,911,512 |
| NIH project number | 5U24DK130164-06 |
| Project ID | NIH-11591404 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with liver cirrhosis and related complications who receive care at participating centers.
✕Less likely to help
Patients not eligible for procedures or interventions studied in the network may see limited direct benefit.
What this research studies
This program coordinates data and scientific activities to better understand liver cirrhosis and its complications, like variceal bleeding, ascites, and hepatic encephalopathy. It builds a network across institutions to share information and standardize how patients are treated and tracked. The goal is to generate knowledge that can translate into better symptoms management and outcomes for people living with cirrhosis.
Why it matters
Potential benefit: If successful, patients with cirrhosis could benefit from more consistent care, better prediction of complications, and improved access to effective treatments.
How similar studies have gone: Previous analyses suggest potential benefits from standardized data coordination, but regionally controlled trial data are still limited.
Where this research is happening
-
Northwestern University
Chicago, United States Active
Researchers
- Principal investigator: Smith, Abigail — Northwestern University
- Study coordinator: Smith, Abigail
Related research
Other NIH-funded projects on the same topics.
-
Liver Cirrhosis Network: Centers for Clinical Research
A multicenter study in people with cirrhosis from different causes (including HIV, NASH, and alcohol-related liver disease) to collect data and samples and test new ways to predict and monitor disease progression.
-
Liver Cirrhosis Network: Mayo Clinic's Clinical Research Center
A Mayo Clinic-led project will follow and help people with compensated cirrhosis, using data, imaging, and a big AI tool to predict when complications may happen and test whether a statin can improve outcomes.
-
Liver Cirrhosis Network: Longitudinal and Clinical Trial Studies
A network-wide NIH study focused on understanding cirrhosis better to prevent complications and improve care for people with advanced liver disease.
-
Liver Cirrhosis Network coordinating cirrhosis studies and a rosuvastatin trial
This project follows people with liver cirrhosis over time and tests whether the cholesterol medicine rosuvastatin helps people with cirrhosis.
-
First-in-class treatment for liver cirrhosis with portal hypertension
A new therapy called XFB19 aims to reduce liver inflammation and scarring in people with advanced liver disease and portal hypertension.
-
Liver cirrhosis network coordinating treatments and patient data
This program brings hospitals together to run and organize tests of treatments and care approaches for people living with liver cirrhosis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.