Liver Cirrhosis Network coordinating cirrhosis studies and a rosuvastatin trial
Liver Cirrhosis Network: Scientific and Data Coordination Center
['FUNDING_OTHER'] · NORTHWESTERN UNIVERSITY · NIH-11473501
This project follows people with liver cirrhosis over time and tests whether the cholesterol medicine rosuvastatin helps people with cirrhosis.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHWESTERN UNIVERSITY (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-11473501 on ClinicalTrials.gov |
What this research studies
You would be part of a large group of people with liver cirrhosis who are followed over time to understand how the disease progresses. A smaller randomized trial within the network gives some participants rosuvastatin and others a matching placebo so researchers can compare outcomes. Northwestern University runs the central data and science coordination, including study design, monitoring, and statistical analysis. The team also manages drug supply and matching placebo pills so the trial can be run safely and fairly.
Who could benefit from this research
Good fit: Adults with a diagnosis of liver cirrhosis who meet the study's health and medication eligibility rules would be the main candidates for participation.
Not a fit: People without liver cirrhosis or those who are medically ineligible (for example due to severe liver failure, conflicting medications, or pregnancy) would not be expected to benefit from joining this trial.
Why it matters
Potential benefit: If successful, this work could show whether rosuvastatin is safe and can reduce complications or improve outcomes for people with cirrhosis.
How similar studies have performed: Observational studies have suggested benefits of statins in cirrhosis but randomized trials are limited, so this trial builds on promising but not yet conclusive prior evidence.
Where this research is happening
CHICAGO, UNITED STATES
- NORTHWESTERN UNIVERSITY — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SMITH, ABIGAIL — NORTHWESTERN UNIVERSITY
- Study coordinator: SMITH, ABIGAIL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.