Improving kidney stone management in young patients
Official title: Personalizing Outcomes of Nephrolithiasis in Youth (PONY) Research Project
Funded at Children's Hosp of Philadelphia · NIH-11159844 · Data updated 2026-11-12
This study is all about finding better ways to help kids and young adults under 21 who have kidney stones, by learning more about how these stones develop and how they feel after surgery, so we can create personalized treatment plans just for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $357,938 |
| NIH project number | 5P20DK140504-02 |
| Project ID | NIH-11159844 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are youth aged 0 to 21 years who have been diagnosed with nephrolithiasis.
✕Less likely to help
Patients over the age of 21 or those without a diagnosis of kidney stones may not benefit from this research.
What this research studies
This research focuses on understanding and improving the management of kidney stones in youth aged 21 and younger. It aims to gather new insights into the natural progression of non-obstructive kidney stones and the experiences of patients after undergoing ureteroscopy surgery. By collaborating with multiple children's hospitals, the project seeks to develop personalized treatment strategies that cater to the unique needs of young patients suffering from this chronic condition. The research will utilize existing data and partnerships to enhance patient-centered care.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for young patients with kidney stones, reducing pain and recurrence rates.
How similar studies have gone: Previous research has shown promise in improving management strategies for chronic conditions in pediatric populations, indicating potential for success in this novel approach.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Chu, David — Children's Hosp of Philadelphia
- Study coordinator: Chu, David
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This study is looking at how calcium levels and acidity in the kidneys affect the formation of calcium-based kidney stones, with the hope of finding new ways to help people prevent these stones from forming.
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Improving kidney stone management in young patients
This study is all about finding better ways to help kids and young adults under 21 who have kidney stones, by learning more about how these stones develop and how they feel after surgery, so we can create tailored treatment plans just for them.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.