Improving health outcomes for veterans with heart failure and kidney disease
Improving Outcomes in Veterans with Heart Failure and Chronic Kidney Disease
This study is looking at how small doses of certain heart and blood pressure medications can help veterans with heart failure and kidney problems feel better, by figuring out who might benefit the most from them based on their health needs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | U.s. Dept/vets Affairs Medical Center NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-10399470 on NIH RePORTER |
What this research studies
This research investigates how low doses of ACE inhibitors and angiotensin receptor blockers can safely improve health outcomes for veterans suffering from heart failure and chronic kidney disease. By analyzing data from a large population of heart failure patients, the study aims to identify which individuals may benefit most from these medications based on their specific health characteristics. The approach includes developing a machine-learning algorithm to personalize treatment plans, potentially reducing the risk of kidney injury while managing heart failure effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with heart failure and chronic kidney disease who are currently receiving or may benefit from ACE inhibitors or angiotensin receptor blockers.
Not a fit: Patients without heart failure or chronic kidney disease, or those who are not veterans, may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatment options for veterans with heart failure and chronic kidney disease.
How similar studies have performed: Previous research has shown that ACE inhibitors and ARBs can reduce mortality in heart failure patients, indicating a foundation for the proposed approach.
Where this research is happening
Washington, United States
- U.s. Dept/vets Affairs Medical Center — Washington, United States (Active)
Researchers
- Principal investigator: Ahmed, Ali — U.s. Dept/vets Affairs Medical Center
- Study coordinator: Ahmed, Ali
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.