Improving Deep Brain Stimulation for Obsessive Compulsive Disorder
Toward Connectomic Deep Brain Stimulation in Obsessive Compulsive Disorder
This study is looking for better ways to use Deep Brain Stimulation to help people with Obsessive Compulsive Disorder who haven't found relief with regular treatments, by focusing on the connections in the brain to find the best spots to stimulate, and patients may get a chance to join trials that could lead to more tailored and effective treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11094839 on NIH RePORTER |
What this research studies
This research investigates how to enhance Deep Brain Stimulation (DBS) for patients with Obsessive Compulsive Disorder (OCD) who do not respond to standard treatments. By focusing on specific brain networks rather than just individual brain regions, the study aims to identify the most effective targets for stimulation. The approach involves analyzing both structural and functional connectivity in the brain to determine which methods best guide DBS. Patients may have the opportunity to participate in trials that could lead to more personalized and effective treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with Obsessive Compulsive Disorder who have not responded to traditional treatment methods.
Not a fit: Patients with OCD who have responded well to conventional treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored treatments for patients with OCD, particularly those who have not benefited from conventional therapies.
How similar studies have performed: Previous research has shown promise in using network-based approaches for DBS, indicating potential for success in this novel application.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Fox, Michael D — Brigham and Women's Hospital
- Study coordinator: Fox, Michael D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.