Improving deep brain stimulation with MRI and AI

Functional Magnetic Resonance Imaging and Deep Learning to Improve Deep Brain Stimulation Therapy

NIH-funded research Ge Medical Systems Information Technologies, INC · NIH-11478774

We use brain scans and artificial intelligence to speed up and personalize deep brain stimulation settings for people getting DBS.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGe Medical Systems Information Technologies, INC NIH-funded
Lab location1 site (Niskayuna, United States)
Project IDNIH-11478774 on NIH RePORTER

What this research studies

The team will use functional MRI scans combined with deep-learning algorithms to predict optimal stimulation contacts and pulse settings. They plan to train models using imaging and clinical response data from patients with movement disorders who have different DBS electrode types. The goal is to reduce the long trial-and-error process that currently takes many clinic visits and months to reach good settings. Participants would provide scans and symptom data while AI-guided programming is compared with usual clinical tuning.

Who could benefit from this research

Good fit: Ideal candidates are people with Parkinson's disease or other movement disorders who are considering or already receiving deep brain stimulation.

Not a fit: People who do not have DBS, are not eligible for DBS, or have implants or health conditions incompatible with MRI or DBS programming may not benefit.

Why it matters

Potential benefit: If successful, this could shorten the time to find the best DBS settings, lower side effects, and improve symptom control.

How similar studies have performed: Some prior work has shown promise using AI and imaging to help DBS programming, but combining functional MRI with deep-learning automated programming remains an emerging approach.

Where this research is happening

Niskayuna, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.