Using deep brain stimulation to treat severe obsessive-compulsive disorder
Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11175481
This study is looking at how deep brain stimulation can help people with severe obsessive-compulsive disorder by targeting specific areas in the brain, and it’s for individuals who are struggling with OCD and want to explore new treatment options.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11175481 on ClinicalTrials.gov |
What this research studies
This research investigates the use of deep brain stimulation (DBS) to precisely target and modulate specific brain circuits involved in severe obsessive-compulsive disorder (OCD). By focusing on a key brain area known as the anterior limb of the internal capsule (ALIC), the study aims to enhance the effectiveness of DBS treatment through advanced imaging techniques and behavioral assessments. Participants will undergo detailed brain mapping and monitoring to identify the most effective stimulation pathways, ultimately improving treatment outcomes for OCD. The research will involve a small group of individuals receiving DBS, who will be closely monitored over time to assess changes in their symptoms and brain activity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with severe obsessive-compulsive disorder who have not responded to traditional treatments.
Not a fit: Patients with mild OCD or those who have not been diagnosed with OCD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for individuals suffering from severe OCD.
How similar studies have performed: Previous research has shown promising results with deep brain stimulation for OCD, but this approach aims to refine and enhance targeting precision, making it a novel advancement.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHOI, KI SUENG — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: CHOI, KI SUENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.