Identifying blood proteins that indicate blood pressure changes during exercise and their link to heart disease.
Official title: Plasma protein markers of the blood pressure response during exercise and their relation to incident hypertension and cardiovascular disease
Funded at Beth Israel Deaconess Medical Center · NIH-11033147 · Data updated 2026-11-12
This study is looking at how your blood pressure changes when you exercise to find hidden heart risks that you might not notice when you're just resting, and it’s for anyone interested in understanding their heart health better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $190,491 |
| NIH project number | 1K23HL177335-01 |
| Project ID | NIH-11033147 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who are at risk for hypertension or cardiovascular disease, particularly those who may not show symptoms at rest.
✕Less likely to help
Patients who already have established cardiovascular disease or those who are not physically able to participate in exercise may not benefit from this research.
What this research studies
This research investigates how blood pressure changes during exercise can reveal hidden cardiovascular risks that are not apparent when a person is at rest. By analyzing blood samples during exercise, the study aims to identify specific proteins that correlate with these blood pressure responses. The researchers will use advanced techniques to measure thousands of unique proteins and assess their relationship with future hypertension and cardiovascular disease in diverse populations. This approach could lead to more accurate risk assessments and better prevention strategies for heart-related conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for predicting and preventing hypertension and cardiovascular disease in patients.
How similar studies have gone: Previous research has shown promise in using exercise-induced changes in blood pressure to identify cardiovascular risks, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Beth Israel Deaconess Medical Center
Boston, United States Active
Researchers
- Principal investigator: Rao, Prashant — Beth Israel Deaconess Medical Center
- Study coordinator: Rao, Prashant
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.