NIH-funded research R01 grant

Integrating heart care into HIV services in Botswana using statins

Official title: Integrating Hypertension and Cardiovascular Disease Care into Existing HIV Service Package in Botswana (InterCARE)-Statin Sub-study

Funded at University of Botswana · NIH-11539151 · Data updated 2026-11-12

This project tests a simple, scalable approach to help people with HIV in Botswana start and stay on statin therapy to prevent heart attacks and strokes.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Botswana
NIH-funded
Lab location1 site (Gaborone, Botswana)
Project startSeptember 1, 2025
Project endJune 30, 2030
Funding year2026
Award (this year)$32,006
NIH project number3R01HL182509-02S1
Project IDNIH-11539151 on NIH RePORTER

Who could benefit from this research

Could help

Adults living with HIV in Botswana who are eligible for statin therapy and are receiving HIV care.

Less likely to help

Individuals without HIV or without indication for statin therapy, or those unable to participate due to medical contraindications, may not benefit.

What this research studies

If people living with HIV can reliably access statin therapy within their existing HIV care, they may have fewer heart problems and better overall health. The study will test a multi-component, community-based way to deliver statins and manage hypertension, using a straightforward age and hypertension status approach rather than complex risk scores. By focusing on a setting with high HIV prevalence, the research aims to show how integrated care can be scaled in resource-limited environments and inform similar efforts in other countries. The results could guide policies to reduce cardiovascular disease among people with HIV in Botswana and beyond.

Why it matters

Potential benefit: If successful, patients with HIV could experience reduced risk of heart attacks and strokes through easier access to and persistence with statin therapy.

How similar studies have gone: Previous work shows that streamlined, integrated care can improve medication uptake in similar settings, though this exact HIV-CVD integration in Botswana is innovative.

Where this research is happening

  • University of Botswana
    Gaborone, Botswana
    Active

Researchers

  • Principal investigator: Mosepele, Mosepele — University of Botswana
  • Study coordinator: Mosepele, Mosepele

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.