NIH-funded research R01 grant

Integrating heart-attack and stroke prevention with HIV care in Botswana

Official title: Integrating Hypertension and Cardiovascular Disease Care into Existing HIV Service Package in Botswana (InterCARE)-Statin Sub-study

Funded at University of Botswana · NIH-11401005 · Data updated 2026-11-12

A study tests a simple, scalable plan to help people with HIV in Botswana get statins to prevent heart problems.

More Hypertension research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Botswana
NIH-funded
Lab location1 site (Gaborone, Botswana)
Project startSeptember 1, 2025
Project endJune 30, 2030
Funding year2026
Award (this year)$462,384
NIH project number5R01HL182509-02
Project IDNIH-11401005 on NIH RePORTER

Who could benefit from this research

Could help

Adults with HIV in Botswana who are eligible for statin therapy and receive HIV care.

Less likely to help

Patients outside the HIV care system or those not evaluating statins may not benefit.

What this research studies

This project will test a practical, multi-component approach inside existing HIV care to boost statin use for people with HIV who are at risk for heart attacks and strokes. It uses a straightforward age plus hypertension approach to identify risk and a differentiated community delivery plan to support statin uptake and ongoing use. The aim is to see how well this integrated strategy works in a real-world setting in Botswana, with outcomes on implementation and reach. If successful, the model could be adapted to similar settings with high HIV prevalence and limited resources.

Why it matters

Potential benefit: If successful, patients with HIV could experience fewer heart-related events through easier, scalable access to statins.

How similar studies have gone: Previous studies show that integrated, scalable strategies can improve preventive care uptake in HIV programs, but results vary by setting.

Where this research is happening

  • University of Botswana
    Gaborone, Botswana
    Active

Researchers

  • Principal investigator: Mosepele, Mosepele — University of Botswana
  • Study coordinator: Mosepele, Mosepele

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.