NIH-funded research NIH-funded research

Gastroparesis data center continues to support kids and adults with gastroparesis

Official title: Continuation of the Scientific Data Research Center (SDRC) of the Gastroparesis Clinical Research Consortium (GpCRC) 4

Funded at Johns Hopkins University · NIH-11384385 · Data updated 2026-11-12

A national research program at Johns Hopkins will keep gathering and sharing data and biospecimens from adults and children with gastroparesis to improve diagnosis, treatment, and care.

More Gastroparesis research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startMay 1, 2006
Project endJuly 31, 2027
Funding year2026
Award (this year)$1,013,427
NIH project number5U24DK074008-20
Project IDNIH-11384385 on NIH RePORTER

Who could benefit from this research

Could help

Adults and children with gastroparesis who enroll in ongoing or future GpCRC studies at participating centers.

Less likely to help

Patients not enrolled in GpCRC studies or not affected by gastroparesis may not directly benefit.

What this research studies

This grant funds the Scientific Data Research Center to coordinate data collection, biospecimens, and multicenter collaboration for gastroparesis patients of all ages. It supports conducting ongoing and new clinical trials (including adult and pediatric studies) and ensures a single IRB oversight to streamline research across centers. The center provides statistical expertise, data management, quality control, and study design support to participating sites. By maintaining centralized resources and shared protocols, patients can contribute to research that aims to improve future therapies and disease understanding.

Why it matters

Potential benefit: If successful, patients may benefit from faster access to new treatments and more precise care through better-designed studies and shared data.

How similar studies have gone: Previous GpCRC efforts have advanced understanding of gastroparesis and driven new trials and biomarker studies; continued data sharing is building on that work.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Shade, David M — Johns Hopkins University
  • Study coordinator: Shade, David M

Related research

Other NIH-funded projects on the same topics.

  • New England Gastroparesis Consortium: Neurobiology of Gastroparesis

    A national project to learn about gastroparesis in children and adults by creating a registry and gathering information from patients to understand symptoms, quality of life, and disease progression.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11583186

  • Pediatric and Young Adult Gastroparesis Registry and Disease Course

    This project follows children, teens, and young adults with symptoms of gastroparesis to learn how their symptoms change over time and what factors are tied to different disease patterns.

    NIH research Texas Tech University Health Sciences Center at El Paso · El Paso, United States · NIH-11575566

  • Pediatric gastroparesis: building a nationwide patient registry

    This grant funds a national registry to study gastroparesis and similar tummy problems in children and teens, with the goal of better understanding how the condition affects their daily lives.

    NIH research Baylor College of Medicine · Houston, United States · NIH-11567122

  • Gut-resident macrophages and gastric function in gastroparesis

    A study in people with gastroparesis to understand how gut macrophages affect stomach movement and gut barrier health, with the hope of finding new ways to treat the condition.

    NIH research University of Nevada Reno · Reno, United States · NIH-11430037

  • Gastric electrical stimulation for stomach pain in gastroparesis

    A new approach tests how adjusting a stomach-stimulating implant may reduce pain for people with gastroparesis.

    NIH research University of Louisville · Louisville, United States · NIH-11416260

  • Peptide therapies for gastroparesis in diabetes

    A new peptide-based treatment is being tested to help people with gastroparesis linked to diabetes by improving stomach emptying and reducing inflammation.

    NIH research Cga Therapeuticals Incorporated · San Diego, United States · NIH-11410020

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.