FGF signaling and vascular remodeling in lung hypertension

Who could benefit from this research

What this research studies

This project focuses on understanding how FGF signaling in blood vessels influences the development of pulmonary hypertension, especially under low-oxygen conditions. The investigator will study endothelial and smooth muscle cell interactions and test adenovirus-delivered FGF as a possible way to regulate abnormal blood vessel changes. The work combines basic biology with potential translational approaches to improve outcomes for patients with pulmonary hypertension. A strong mentorship plan and access to a rich research environment at WUSM support the goal of advancing toward independent physician-scientist status.

Why it matters

Where this research is happening

• Washington University
  Saint Louis, United States Active

Researchers

• Principal investigator: Woo, Kelvin — Washington University
• Study coordinator: Woo, Kelvin

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.