Cedars‑Sinai program on diabetes that follows acute pancreatitis
Official title: Cedars Sinai Clinical Center of the Type 1 Diabetes in Acute Pancreatitis Consortium
Funded at Cedars-Sinai Medical Center · NIH-11234961 · Data updated 2026-11-12
This program follows people who had acute pancreatitis to find biological and genetic signs that predict who will develop diabetes afterward.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 16, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $511,000 |
| NIH project number | 2U01DK127403-06 |
| Project ID | NIH-11234961 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults who have had acute pancreatitis, especially those with repeated episodes or new-onset diabetes after pancreatitis.
✕Less likely to help
People without a history of acute pancreatitis or whose diabetes is clearly typical type 2 unrelated to pancreatic injury are unlikely to benefit directly from this program.
What this research studies
If you had acute pancreatitis, this program follows you over time to see who develops diabetes and why. The team continues enrolling people into the DREAM cohort and runs approved ancillary studies to collect blood, genetic data, and clinical information. Researchers use those samples and health records to identify biomarkers and molecular pathways that link acute pancreatitis to recurrent or chronic pancreatic disease and to diabetes. The goal is to learn patterns that could help predict risk or point to prevention strategies.
Why it matters
Potential benefit: If successful, this work could help identify people at high risk for diabetes after pancreatitis earlier and guide steps to prevent or better manage it.
How similar studies have gone: Other cohort and biomarker studies have suggested links between pancreatitis and later diabetes, but linking specific genetics and pathways remains an emerging area that this consortium is expanding.
Where this research is happening
-
Cedars-Sinai Medical Center
Los Angeles, United States Active
Researchers
- Principal investigator: Goodarzi, Mark — Cedars-Sinai Medical Center
- Study coordinator: Goodarzi, Mark
Related research
Other NIH-funded projects on the same topics.
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Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
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Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
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Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
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Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest
A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.
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Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai
This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.
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Understanding how acute pancreatitis may lead to type 1 diabetes
This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it aims to find early warning signs and risk factors to help identify people who could be at risk for developing diabetes after pancreatitis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.