Developing new vaccines to fight tuberculosis

Advancing Innovative Next_generation Heterologous Vaccines Against Tuberculosis

NIH-funded research Texas Biomedical Research Institute · NIH-10834753

This study is working on new and better vaccines for tuberculosis (TB) to help protect people more effectively than the current vaccine, so that patients can have improved options for preventing this serious disease.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTexas Biomedical Research Institute NIH-funded
Lab location1 site (San Antonio, United States)
Project IDNIH-10834753 on NIH RePORTER

What this research studies

This research focuses on creating innovative vaccines to combat tuberculosis (TB), a disease that has claimed millions of lives. The project aims to identify and develop new vaccine candidates that can provide better protection against TB than the currently available vaccine. Researchers will explore combining specific protein antigens with new adjuvants to enhance immune responses and utilize novel RNA technology to create effective vaccines. Patients may benefit from improved vaccination options that could lead to better prevention of TB.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at high risk for tuberculosis, including those in endemic regions or with compromised immune systems.

Not a fit: Patients who are already infected with tuberculosis and require immediate treatment may not benefit directly from this vaccine-focused research.

Why it matters

Potential benefit: If successful, this research could lead to more effective vaccines that significantly reduce the incidence and transmission of tuberculosis.

How similar studies have performed: Previous research has shown promise in developing new vaccine strategies for tuberculosis, indicating potential for success in this innovative approach.

Where this research is happening

San Antonio, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.