Screening for latent tuberculosis in school contacts of active patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the prevalence of Mycobacterium tuberculosis infection among students who have been in close contact with active tuberculosis patients. It will evaluate risk factors associated with tuberculosis infection and conduct a health economic analysis of the screening strategy using the QuantiFERON-TB Gold test. The study focuses on students aged 13 and older from junior middle school to university who have been in close contact with active cases. The findings could help improve screening strategies in educational settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 13 years old or above;
* Students in junior middle school, high school and university;
* Close contact of school active tuberculosis case (e.g. in the same classroom, in the same dormitory);
* Himself/herself (together with his/her guardian for age under 18 years old) willing to participate in trial and sign informed consent.

Exclusion Criteria:

* Current clinical or sputum culture confirmed active tuberculosis
* Have completed a full course of treatment for ATB or LTBI

Where it's running

• Xinpu New Area Center of Disease Control
  Zunyi, Guiyang, China Recruiting
• Dafang Center for Disease Control and Prevention
  Bijie, Guizhou, China Recruiting
• Qixingguan Center for Disease Control and Prevention
  Bijie, Guizhou, China Recruiting
• Nayong Center for Disease Control and Prevention
  Bijie, Guizhou, China Recruiting
• Hezhang Center for Disease Control
  Bijie, Guizhou, China Recruiting
• Jinsha Center for Disease Control
  Bijie, Guizhou, China Recruiting

Study contacts

• Principal investigator: Wenhong Zhang, PhD — Huashan Hospital
• Study coordinator: Qiaoling Ruan, PhD
• Email: ruan_qiao_ling@fudan.edu.cn
• Phone: 13661856002

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.