NIH-funded research R21 grant

Biometric wearables to predict opioid relapse

Official title: Development of a biometrics-based platform to predict relapse

Funded at Mclean Hospital · NIH-11302974 · Data updated 2026-11-12

A brief study will test a wearable-based tool to forecast relapse risk in adults with opioid use disorder to help prevent overdose.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMclean Hospital
NIH-funded
Lab location1 site (Belmont, United States)
Project startMay 15, 2026
Project endApril 30, 2028
Funding year2026
Award (this year)$451,000
NIH project number1R21DA062815-01A1
Project IDNIH-11302974 on NIH RePORTER

Who could benefit from this research

Could help

Adults with opioid use disorder who are seeking treatment or in recovery and willing to use wearable biosensors.

Less likely to help

Individuals not using opioids or not willing to wear biosensors may not benefit.

What this research studies

This project uses wearable biosensors and real-time data to identify patterns that might signal an upcoming relapse in adults with opioid use disorder. The team at McLean Hospital will collect physiological and behavioral signals from participants and apply secure algorithms to detect relapse risk. If successful, this approach could lead to timely alerts and interventions to prevent overdoses. The study is in early stages and focuses on translating wearable data into practical insights for people seeking treatment. Participants will be closely monitored and supported by clinicians throughout the study period.

Why it matters

Potential benefit: If successful, the approach could provide real-time relapse warnings to help prevent overdoses and save lives.

How similar studies have gone: Wearable biosensors have shown promise in health monitoring, but this specific relapse-prediction approach in opioid use disorder is exploratory and is not yet proven.

Where this research is happening

  • Mclean Hospital
    Belmont, United States
    Active

Researchers

  • Principal investigator: Lukas, Scott E — Mclean Hospital
  • Study coordinator: Lukas, Scott E

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.