Advancing Pediatric Gastroparesis Care and Understanding
Official title: Advancing Clinical Science in Pediatric Gastroparesis
Funded at Baylor College of Medicine · NIH-11384700 · Data updated 2026-11-12
A long-running NIH grant aims to improve how gastroparesis affects children and young people, by building better patient-reported measures and understanding what makes the disease worse.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 25, 2016 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $257,666 |
| NIH project number | 5U01DK112194-10 |
| Project ID | NIH-11384700 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents with gastroparesis or functional dyspepsia, and their families, who participate in patient-reported outcomes assessments.
✕Less likely to help
Some participants may not experience immediate changes in treatment based on the questionnaires alone, though their data contribute to broader knowledge.
What this research studies
This project continues a pediatric GP research program to create and validate tools that measure quality of life and symptoms in kids with gastroparesis and pediatric functional dyspepsia. Researchers will collect data from children and young people to refine a pediatric GP symptom module and a pediatric QoL module, then test them in real-world settings. The work focuses on identifying factors that influence disease severity and patient well‑being, with an emphasis on how symptoms overlap with FD in youth. The study builds on prior pediatric registry work and uses field testing, qualitative methods, and patient-reported outcomes to guide future care strategies.
Why it matters
Potential benefit: If successful, the project could yield validated tools that help clinicians monitor GP in children and tailor treatments to improve quality of life.
How similar studies have gone: Previous pediatric GP registry work has informed tool development, with ongoing efforts to validate and expand these measures.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Preidis, Geoffrey a — Baylor College of Medicine
- Study coordinator: Preidis, Geoffrey a
Related research
Other NIH-funded projects on the same topics.
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New England Gastroparesis Consortium: Neurobiology of Gastroparesis
A national project to learn about gastroparesis in children and adults by creating a registry and gathering information from patients to understand symptoms, quality of life, and disease progression.
-
Pediatric and Young Adult Gastroparesis Registry and Disease Course
This project follows children, teens, and young adults with symptoms of gastroparesis to learn how their symptoms change over time and what factors are tied to different disease patterns.
-
Pediatric gastroparesis: building a nationwide patient registry
This grant funds a national registry to study gastroparesis and similar tummy problems in children and teens, with the goal of better understanding how the condition affects their daily lives.
-
Gut-resident macrophages and gastric function in gastroparesis
A study in people with gastroparesis to understand how gut macrophages affect stomach movement and gut barrier health, with the hope of finding new ways to treat the condition.
-
Gastric electrical stimulation for stomach pain in gastroparesis
A new approach tests how adjusting a stomach-stimulating implant may reduce pain for people with gastroparesis.
-
Peptide therapies for gastroparesis in diabetes
A new peptide-based treatment is being tested to help people with gastroparesis linked to diabetes by improving stomach emptying and reducing inflammation.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.