Condition

Unipolar Depression clinical trials and research

• 8Clinical trials
• 5Countries

Newest Unipolar Depression clinical trials

All recruiting trials (8)

• RNA editing to predict antidepressant response in unipolar and bipolar depression

  This project tests whether changes in RNA editing can predict how adults with unipolar or bipolar depression respond to antidepressant treatment.

  Recruiting Phase 4 Mayo Clinic · Rochester, Minnesota · NCT07266545

• Psilocybin-assisted therapy for major depression in people with non-small cell lung cancer

  This phase II trial tests whether a single oral dose of psilocybin combined with psychotherapy can reduce moderate-to-severe depression in adults with non-small cell lung cancer.

  Recruiting Phase 2 Ohio State University Comprehensive Cancer Center · Columbus, Ohio · NCT07216404

• Transcranial direct current stimulation plus mindfulness for unipolar depression

  This project will test whether adding transcranial direct current stimulation (tDCS) to remotely delivered mindfulness helps adults with unipolar depression feel less depressed.

  Recruiting Soterix Medical · Woodbridge, New Jersey · NCT07042217

• EmoDTx mood-monitoring app for adults with unipolar depression

  This project will test whether the EmoDTx app, which analyzes facial expressions, can track mood in adults with unipolar depression and align with standard questionnaires.

  Recruiting at 2 sites Emobot · Changé, France and 1 other locations · NCT06860165

• Yoga for improving thinking skills in people with unipolar depression

  This study is testing if regular yoga sessions can help people who have recovered from unipolar depression improve their thinking skills.

  Recruiting University of Pittsburgh · Bengaluru, Karnataka · NCT06472492

• Effects of theta burst stimulation on sleep and fatigue in depression

  This study is testing if two types of brain stimulation can improve sleep and reduce tiredness in people with depression.

  Recruiting Jagiellonian University · Warsaw · NCT06371352

• Using rTMS to treat mood and cognitive symptoms of depression

  This study is testing if a new way of using brain stimulation can help improve mood and thinking problems in people with unipolar and bipolar depression who haven't found relief from regular treatments.

  Recruiting Jagiellonian University · Krakow · NCT06363981

• Using Enoxolone to Improve Treatment Response in Major Depression

  This study is testing whether enoxolone, a compound from licorice, can help people with major depression who haven't responded to other treatments feel better.

  Recruiting Phase 1/2 Philipps University Marburg · Marburg, Hesse · NCT05570110

Related topics

Quick answers

How many Unipolar Depression clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (3 trials), Poland (2 trials), Germany (1 trial), India (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1, Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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