Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

Yoga for improving thinking skills in people with unipolar depression

Official title: A Randomized Control Trial Involving Yoga Intervention for Cognitive Enhancement in Persons With Remitted Unipolar Depression

Run by University of Pittsburgh · NCT06472492 · Data updated 2026-11-12

This study is testing if regular yoga sessions can help people who have recovered from unipolar depression improve their thinking skills.

Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment32 (estimated)
SponsorUniversity of Pittsburgh
Academic / other
Locations1 site (Bengaluru, Karnataka)
StatusRecruiting
StartedMay 17, 2024
Main results expectedDecember 31, 2026
Study endsJune 30, 2027
Registry record updatedMarch 27, 2026
Trial IDNCT06472492 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 60 who have experienced at least one depressive episode that is currently in remission.

Probably not a fit

Patients with comorbid psychiatric conditions such as psychosis, bipolar disorder, or significant cognitive impairment may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates whether specific yoga practices can enhance cognitive abilities in individuals who have experienced unipolar depression and are currently in remission. It recognizes that cognitive deficits often persist even after depressive episodes have resolved, affecting executive functions such as decision-making and focus. Participants will engage in regular yoga sessions alongside their ongoing treatment for depression, with the aim of improving their cognitive performance. Screening for eligibility will involve a verbal questionnaire to assess symptoms and suitability for the study.

Why it matters

Potential benefit: If successful, this approach could provide a non-pharmacological method to improve cognitive function in individuals recovering from unipolar depression.

How similar studies have gone: Previous studies have shown that yoga can help improve cognitive functions in the general population, suggesting potential for success in this specific application.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age more than 18years and less than 60 years
* H/o at least one depressive episode which is under remission and at the time of examination and throughout the study duration,
* Informed Consent

Exclusion Criteria:

* Comorbid Psychosis, OCD, Bipolar disorder
* Comorbid ADHD, IDD
* Comorbid substance dependence (except tobacco)
* Comorbid major or minor cognitive impairment,
* Bi temporal ECT within 6 months
* Past yoga practice - regularly for 1 month within 3 months Pregnancy

Where it's running

  • National Institute of Mental Health and Neuroscience (NIMHANS)
    Bengaluru, Karnataka, India
    Recruiting

Study contacts

  • Principal investigator: Vishwajit L Nimgaonkar, MD, PhD — University of Pittsburgh
  • Study coordinator: Vishwajit L Nimgaonkar
  • Email: vishwajitnl@upmc.edu
  • Phone: 4127265164

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.