Condition

STEMI clinical trials and research

• 13Clinical trials
• 3NIH research projects
• 17Countries

Newest STEMI clinical trials

All recruiting trials (13)

• Early single antiplatelet therapy after IVUS-guided PCI in ACS

  This study tests whether stopping aspirin early and continuing a potent P2Y12 inhibitor alone is safe and effective after IVUS-guided PCI in people with acute coronary syndrome.

  Recruiting Phase 4 Gyeongsang National University Hospital · Jinju, Gyeongsangnam-do · NCT07684742

• Drug-coated balloon treatment during emergency angioplasty for STEMI

  This registry will try using drug-coated balloons instead of stents during emergency PCI for people with ST-elevation heart attacks to see how the procedure and patient outcomes compare.

  Recruiting Medical University of Vienna · Vienna · NCT07436429

• Early intravenous landiolol to limit heart muscle damage after STEMI

  This study tries early IV landiolol versus standard oral beta-blockers to see if it reduces the amount of heart muscle damage in adults with STEMI who undergo primary PCI.

  Recruiting Aristotle University Of Thessaloniki · Thessaloniki, Thessaloniki · NCT07293832

• Retinal OCTA to detect tiny blood vessel problems in people with MINOCA

  This project will use a quick retinal OCTA scan to see if tiny blood vessel changes differ in people with MINOCA compared with heart attack patients who have blocked arteries and with healthy volunteers.

  Recruiting University of Pisa · Pisa, Pisa · NCT07055152

• Long-term changes in left ventricular function after STEMI

  We will test whether detailed heart imaging and blood tests can track long-term changes in heart structure and function in people who had a STEMI treated with primary PCI.

  Recruiting University of Pisa · Pisa, Pisa · NCT07041840

• Targeted look at residual inflammation after a heart attack

  This project will test whether the neutrophil-to-lymphocyte ratio (NLR) from the first routine blood draw can help predict risk of death in adults (18–85) after an acute coronary syndrome treated with PCI.

  Recruiting University Hospital Centre Mother Teresa · Tirana · NCT07026708

• Assessing no-reflow in STEMI patients after tirofiban treatment

  This study is testing if the drug tirofiban can help prevent no-reflow in patients with a severe heart attack who have had a procedure to open their blocked arteries.

  Recruiting Kafrelsheikh University · Kafr ash Shaykh, Kafrelsheikh · NCT06966674

• Breisgau PHENO-HEART MI: Understanding Heart Attack Biology in Adults

  This observational study in adults with STEMI or NSTEMI looks at the body’s immune response after a heart attack to understand how tissue damage and healing affect outcomes.

  Recruiting University Hospital Freiburg · Freiburg im Breisgau · NCT06166407

• Using Dapagliflozin to Prevent Heart Changes After a Heart Attack

  This study tests if the medication dapagliflozin can help prevent heart problems in people who have had a heart attack and have some heart weakness.

  Recruiting Phase 3 Assistance Publique - Hôpitaux de Paris · Paris · NCT05764057

• Registry to optimize management and outcomes for patients with acute myocardial infarction

  This study is looking at how well different treatments work for patients who have had a heart attack and received a specific procedure called PCI, to see what helps them recover better.

  Recruiting Luzerner Kantonsspital · Lucerne · NCT04988672

• Using Remote Ischaemic Conditioning to Improve Outcomes in STEMI Patients in Africa

  This study is testing if a treatment called Remote Ischaemic Conditioning can help reduce deaths and heart failure in people with a severe heart attack in Africa.

  Recruiting at 20 sites University of Cape Town · Mombasa, Mombasa County and 19 other locations · NCT04813159

• Low-dose thrombolytic therapy for heart attack patients

  This study is testing if a low dose of a clot-busting drug can help heart attack patients recover better after their treatment.

  Recruiting at 14 sites Phase 3 University of Sydney · Bankstown, New South Wales and 21 other locations · NCT03998319

• National observatory for interventional cardiology in France

  This study is looking at how heart procedures are done in different hospitals in France to see how they can improve care for patients who have had heart tests or treatments.

  Recruiting at 13 sites Club Régional des Angioplasticiens de la région Centre · Le Coudray, Eure Et Loire and 14 other locations · NCT02778724

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• AI screening to speed STEMI diagnosis in ED patients

  A Stanford-led project uses artificial intelligence to quickly identify STEMI among ED patients with acute coronary syndrome to reduce treatment delays and improve outcomes.

  NIH research Stanford University · Stanford, United States · NIH-11262229

• Improving heart attack diagnosis using artificial intelligence

  This study is working on using artificial intelligence to help emergency departments quickly and accurately identify heart attacks, especially for women and people of color who might not get diagnosed as fast, so everyone can receive the care they need within the first 10 minutes of arriving.

  NIH research Stanford University · Stanford, United States · NIH-10999429

• Improving emergency care for heart attack patients in rural areas

  This study is working on a helpful mobile app for paramedics in rural areas to make sure they can give the best care to heart attack patients before they get to the hospital, aiming to speed up treatment and improve outcomes.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-10916526

Related topics

Quick answers

How many STEMI clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 17 countries. The most sites are in France (2 trials), Italy (2 trials), Australia (1 trial), New Zealand (1 trial), Kenya (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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