Assessing no-reflow in STEMI patients after tirofiban treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the occurrence of no-reflow in patients experiencing ST-segment-elevation myocardial infarction (STEMI) after receiving intracoronary administration of the glycoprotein IIb/IIIa inhibitor tirofiban. The research focuses on patients who have undergone primary percutaneous coronary intervention (PCI) to open blocked coronary arteries. By investigating the effectiveness of tirofiban in preventing no-reflow, the study aims to improve patient outcomes following acute coronary events.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years old.
* Both sexes.
* Patients with STEMI. ST-segment elevated myocardial infarction is defined as typical chest pain \>30 minutes with ST-segment elevation of \>1 mm in at least 2 consecutive leads on the electrocardiogram or new-onset left bundle brunch block.

Exclusion Criteria:

* Treatment with thrombolytic drugs in the previous 24 hours.
* Known malignancy.
* Thrombocytopenia.
* End-stage liver disease.
* Cardiogenic shock.
* Renal failure with glomerular filtration\<30 ml/min.
* Contraindication for the use of tirofiban.

Where it's running

• Kafrelsheikh University
  Kafr ash Shaykh, Kafrelsheikh, Egypt Recruiting

Study contacts

• Study coordinator: Mohammed A Hammad, MD
• Email: drhammad879@gmail.com
• Phone: 00201015928694

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.