Long-term changes in left ventricular function after STEMI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Patients with STEMI treated with primary percutaneous coronary intervention were followed prospectively with comprehensive clinical data, serial blood biomarkers (NT-proBNP, troponin, leukocyte count, CRP, IL-1, IL-6), electrocardiography, transthoracic echocardiography at admission and before discharge, and cardiac magnetic resonance imaging before discharge and at six months. CMR was used to characterize intramyocardial hemorrhage, microvascular obstruction, infarct size, area at risk, and salvaged myocardium, while echocardiography provided serial volumetric and ejection fraction measurements. Left ventricular remodeling (LVR) was defined by predefined changes in end-diastolic and end-systolic volumes, sphericity index, new concentric hypertrophy, or a drop in LVEF. The protocol excluded patients with contraindications to CMR and was conducted at the University of Pisa (Cisanello Hospital) with a six-month imaging and laboratory follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* STEMI

Exclusion Criteria:

* Contraindication to CMR imaging

Where it's running

• University of Pisa, Cisanello Hospital
  Pisa, Pisa, Italy Recruiting

Study contacts

• Study coordinator: Mattia Alberti, Dr
• Email: mattia.alberti96@outlook.it
• Phone: +393271946335

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.