Condition

Stage I Prostate Cancer AJCC v8 clinical trials and research

• 11Clinical trials
• 1Country

Newest Stage I Prostate Cancer AJCC v8 clinical trials

All recruiting trials (11)

• MRI or CT planning to guide high-dose-rate prostate brachytherapy

  This trial tests whether adding an MRI to CT-based treatment planning for HDR prostate brachytherapy changes urinary side effects in men with localized prostate cancer.

  Recruiting at 3 sites Emory University · Atlanta, Georgia and 2 other locations · NCT07859722

• Exercise after pelvic radiation to see if it lowers colorectal cancer risk

  This study tests whether regular walking therapy after pelvic radiation for prostate cancer can influence markers of colorectal cancer in colon tissue and blood.

  Recruiting at 2 sites City of Hope Medical Center · Duarte, California and 1 other locations · NCT07790718

• Image-guided adaptive stereotactic body radiation therapy for localized prostate cancer

  This trial tests whether daily, real-time adaptive image-guided SBRT causes fewer urinary and other side effects than standard non-adaptive SBRT for men with localized prostate cancer.

  Recruiting Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT07276438

• Wrapping nerves with a multi-layer perinatal tissue graft during prostate removal

  This trial will test whether wrapping the nerves with a multi-layer perinatal tissue allograft during nerve-sparing robotic prostate removal helps men with localized prostate cancer keep erectile and urinary function.

  Recruiting Mayo Clinic · Jacksonville, Florida · NCT06940271

• Testosterone therapy for men with low testosterone and localized prostate cancer on active surveillance

  This study is testing if testosterone therapy can help men with low testosterone and localized prostate cancer feel better and stay safe while they are being monitored for their cancer.

  Recruiting Phase 4 Roswell Park Cancer Institute · Buffalo, New York · NCT06733350

• Using advanced imaging to predict lymph node spread in high-risk prostate cancer

  This study is testing a new imaging method to see if it can help doctors predict whether high-risk prostate cancer has spread to lymph nodes before surgery.

  Recruiting Mayo Clinic · Jacksonville, Florida · NCT06389786

• Adaptive radiation therapy for localized prostate cancer

  This study is testing a new type of radiation therapy for localized prostate cancer to see if it can improve patients' quality of life compared to standard treatment.

  Recruiting at 5 sites Mayo Clinic · Albert Lea, Minnesota and 4 other locations · NCT06325046

• Focal ablation treatments for localized prostate cancer

  This study is testing if new focal treatments like cryotherapy and high-intensity ultrasound can effectively treat localized prostate cancer in men and improve their urinary and sexual function over time.

  Recruiting University of California, Davis · Sacramento, California · NCT06178354

• Using advanced imaging to detect prostate cancer in men eligible for active surveillance

  This study is testing a new type of imaging to see if it can better find serious prostate cancer in men who are being monitored for low-risk disease.

  Recruiting Early Phase 1 Northwestern University · Chicago, Illinois · NCT05852041

• High-dose vitamin D for bone health in older prostate cancer patients on hormone therapy

  This study is testing if high-dose vitamin D can help older prostate cancer patients on hormone therapy keep their bones strong and reduce the risk of falls and fractures.

  Recruiting at 51 sites Phase 3 University of Rochester · Newark, Delaware and 50 other locations · NCT05838716

• MRI-guided ultrasound treatment for intermediate grade prostate cancer

  This study is testing a new ultrasound treatment for men aged 45 to 80 with intermediate grade prostate cancer to see if it safely destroys tumor cells and helps them recover better than surgery.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT05438563

Related topics

Quick answers

How many Stage I Prostate Cancer AJCC v8 clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Early Phase 1: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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