Condition

Stage IV Non-small Cell Lung Cancer clinical trials and research

• 7Clinical trials
• 4Countries

Newest Stage IV Non-small Cell Lung Cancer clinical trials

All recruiting trials (7)

• Cemiplimab guided by ctDNA levels (PALACE)

  This study will see if starting adults with advanced (stage IIIB/C or IV) non-small cell lung cancer and PD-L1 ≥50% on cemiplimab, then using ctDNA and early scans to decide whether to add chemotherapy, can improve overall survival.

  Recruiting at 19 sites Phase 2 Fundación GECP · Alicante, Alicante and 19 other locations · NCT06917573

• Analyzing tumor DNA to predict response to cancer treatment in lung cancer patients

  This study is testing if measuring tumor DNA in the blood can help predict how well lung cancer patients respond to a specific treatment called Tyrosine Kinase Inhibitors.

  Recruiting Gene Solutions · Ho Chi Minh City · NCT06167460

• Using enhanced immune cells to treat specific types of lung cancer

  This study is testing a new treatment using special immune cells and a drug to see if it can help people with advanced lung cancer that has certain genetic changes and hasn’t improved with previous treatments.

  Recruiting Phase 1 H. Lee Moffitt Cancer Center and Research Institute · Tampa, Florida · NCT05681780

• Infusion of IOV-4001 for advanced melanoma and lung cancer

  This study is testing a new treatment called IOV-4001 to see if it can help adults with advanced melanoma and lung cancer by targeting and killing their tumor cells.

  Recruiting at 10 sites Phase 1/2 Iovance Biotherapeutics, Inc. · Los Angeles, California and 10 other locations · NCT05361174

• Supportive care model for patients with advanced lung cancer

  This study is testing a new supportive care program for people with advanced lung cancer to see if it helps them feel less stressed and more confident about managing their condition compared to standard care.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT04900935

• New radiotherapy approach for advanced lung cancer

  This study is testing a new type of radiotherapy for patients with advanced lung cancer who can't have regular treatment to see if it can help them live longer and feel better.

  Recruiting Danish Lung Cancer Group · Aarhus · NCT03742687

• Improving survival in patients with advanced lung cancer in Ohio

  This study is testing a new approach to help people with advanced lung cancer in Ohio live longer and feel better by using advanced genetic and immune system tests to guide their treatment.

  Recruiting Ohio State University Comprehensive Cancer Center · Columbus, Ohio · NCT03199651

Related topics

Quick answers

How many Stage IV Non-small Cell Lung Cancer clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (4 trials), Vietnam (1 trial), Denmark (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 2: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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