Condition

Stage IIIC Lung Cancer AJCC v8 clinical trials and research

• 10Clinical trials
• 1Country

Newest Stage IIIC Lung Cancer AJCC v8 clinical trials

All recruiting trials (10)

• Combining chemotherapy with immunotherapy for older adults with advanced lung cancer

  This study is testing if adding chemotherapy to immunotherapy can help older adults with advanced lung cancer live longer and feel better compared to just using immunotherapy alone.

  Recruiting at 271 sites Phase 3 National Cancer Institute (NCI) · Fayetteville, Arkansas and 329 other locations · NCT06096844

• Combining SX-682 and Pembrolizumab for Advanced Lung Cancer Treatment

  This study is testing if a new oral medication called SX-682, when combined with the IV drug pembrolizumab, can help people with advanced lung cancer feel better and improve their treatment outcomes.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT05570825

• Personalized vaccine combined with pembrolizumab for advanced solid tumors

  This study is testing a new personalized cancer vaccine combined with pembrolizumab to see if it helps people with advanced solid tumors fight their cancer better.

  Recruiting Phase 1/2 Mayo Clinic · Jacksonville, Florida · NCT05269381

• Using papaverine with chemoradiation to treat advanced non-small cell lung cancer

  This study is testing the best dose of papaverine combined with chemotherapy and radiation to see if it helps people with advanced non-small cell lung cancer live longer and control their tumors better.

  Recruiting at 2 sites Phase 1 Ohio State University Comprehensive Cancer Center · Duarte, California and 1 other locations · NCT05136846

• Assessing heart health in lung cancer patients receiving personalized chemoradiation

  This study is testing how personalized chemoradiation treatment for lung cancer affects heart health in patients and if adjusting the treatment can help reduce heart disease risk.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT05010109

• Combining local therapy and durvalumab for advanced lung cancer after initial treatment

  This study is testing whether combining local treatments like surgery or radiation with the immunotherapy durvalumab can help people with advanced lung cancer live longer and feel better after their initial treatment.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04892953

• Using canakinumab to prevent lung cancer in high-risk patients

  This study is testing if a medication called canakinumab can help prevent lung cancer in people who have high-risk lung nodules.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04789681

• Avapritinib for treating advanced solid tumors with specific mutations

  This study is testing if a new drug called avapritinib can help people with advanced solid tumors that have specific mutations feel better and live longer after other treatments haven't worked.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04771520

• Yoga intervention to improve physical performance and quality of life for cancer patients and their caregivers

  This study tests whether a yoga program can help improve physical performance and quality of life for cancer patients and their caregivers during radiotherapy.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT03948100

• Exploring gut microbiome and fecal transplant effects on GI issues in cancer patients

  This study is testing how the gut bacteria affect stomach issues in cancer patients receiving certain treatments and whether a stool transplant can help relieve those problems.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT03819296

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Quick answers

How many Stage IIIC Lung Cancer AJCC v8 clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 2, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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