Condition
Stage I Rectal Cancer AJCC v8 clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Stage I Rectal Cancer AJCC v8 clinical trials that are recruiting, at sites in 2 countries (most in United States (4), Puerto Rico (1)). By phase: Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest Stage I Rectal Cancer AJCC v8 clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Zanidatamab given before surgery for HER2-positive colon or rectal cancer | Phase 2 | Atlanta, Georgia and 3 other locations | Recruiting | Feb 12, 2026 |
| Family genetics: who shares test results with relatives | — | Birmingham, Alabama and 364 other locations | Recruiting | Aug 27, 2025 |
| Mobile health intervention to help colorectal cancer survivors and their caregivers follow lifestyle recommendations | — | Columbus, Ohio | Recruiting | Dec 24, 2024 |
| Evaluating quality of life after surgery for rectal cancer | — | Houston, Texas | Recruiting | Apr 8, 2014 |
All recruiting trials (4)
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Zanidatamab given before surgery for HER2-positive colon or rectal cancer
This tests whether giving zanidatamab before surgery helps adults with HER2-positive, RAS‑wildtype colon or rectal cancer who are planned for curative treatment.
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Family genetics: who shares test results with relatives
This study tests whether letting patients share genetic results with their relatives is as good as doctors sharing the results to help first-degree relatives get genetic testing for hereditary cancer risk.
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Mobile health intervention to help colorectal cancer survivors and their caregivers follow lifestyle recommendations
This study is testing a new mobile app to help colorectal cancer survivors and their caregivers stick to healthy lifestyle habits through goal-setting and coaching.
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Evaluating quality of life after surgery for rectal cancer
This study looks at how surgery for rectal cancer affects the quality of life for patients over time, comparing those who received radiation therapy to those who didn’t.
Related topics
Quick answers
How many Stage I Rectal Cancer AJCC v8 clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (4 trials), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.