Condition
Rectal Carcinoma clinical trials and research
As of November 12, 2026, Find a Trial lists 7 Rectal Carcinoma clinical trials that are recruiting, at sites in 5 countries (most in United States (5), Guam (1), Puerto Rico (1)). By phase: Phase 2 (2), Phase 2/3 (1), Early Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 5Countries
Newest Rectal Carcinoma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Vaginal DHEA to improve vaginal health after pelvic radiation | Phase 2 | Columbus, Ohio | Recruiting | Feb 12, 2026 |
| Zanidatamab given before surgery for HER2-positive colon or rectal cancer | Phase 2 | Atlanta, Georgia and 3 other locations | Recruiting | Feb 12, 2026 |
| Using the PAGODA algorithm to guide FOLFOX dose changes and reduce unplanned chemotherapy delays | — | Fairbanks, Alaska and 397 other locations | Recruiting | Dec 16, 2025 |
| Using advanced CT imaging to assess rectal cancer growth | — | Rochester, Minnesota | Recruiting | May 11, 2025 |
| Imaging study using two antibody fragments in patients with solid tumors | Early Phase 1 | Groningen, Provincie Groningen | Recruiting | Oct 17, 2024 |
| Bowel management program for treating low anterior resection syndrome in rectal cancer patients | — | Columbus, Ohio | Recruiting | May 22, 2024 |
| Tailored management for locally advanced rectal cancer | Phase 2/3 | Marseille, Bouches Du Rhône and 29 other locations | Recruiting | Feb 11, 2021 |
All recruiting trials (7)
-
Vaginal DHEA to improve vaginal health after pelvic radiation
This phase II trial tests whether daily vaginal DHEA can help reduce vaginal dryness, pain, and related symptoms in menopausal women after radiation for gynecologic, anal, or rectal cancers.
-
Zanidatamab given before surgery for HER2-positive colon or rectal cancer
This tests whether giving zanidatamab before surgery helps adults with HER2-positive, RAS‑wildtype colon or rectal cancer who are planned for curative treatment.
-
Using the PAGODA algorithm to guide FOLFOX dose changes and reduce unplanned chemotherapy delays
This trial will test whether using the PAGODA algorithm to guide dose changes during FOLFOX chemotherapy for people with gastrointestinal cancers can reduce unplanned treatment delays.
-
Using advanced CT imaging to assess rectal cancer growth
This study is testing a new type of CT scan to see if it can better track the growth of rectal cancer compared to regular MRI scans in adults who have been diagnosed with the disease.
-
Imaging study using two antibody fragments in patients with solid tumors
This study is testing two special antibody fragments in people with solid tumors to see how well they target cancer cells and how they move through the body.
-
Bowel management program for treating low anterior resection syndrome in rectal cancer patients
This study is testing a bowel management program using special enemas to see if it helps people with low anterior resection syndrome after rectal cancer surgery feel better compared to standard treatment.
-
Tailored management for locally advanced rectal cancer
This study is testing a personalized treatment plan for people with locally advanced rectal cancer to see if early responses to chemotherapy can help decide whether they should have surgery right away or combine it with radiation therapy.
Related topics
Quick answers
How many Rectal Carcinoma clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in United States (5 trials), Guam (1 trial), Puerto Rico (1 trial), France (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 2/3: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.