Condition

Small Cell Lung Carcinoma clinical trials and research

• 19Clinical trials
• 4NIH research projects
• 20Countries

Newest Small Cell Lung Carcinoma clinical trials

All recruiting trials (19)

• Multidisciplinary treatment planning for older people with lung cancer

  We will test a team-based approach that uses geriatric assessments to create personalized treatment plans for people aged 60–90 with newly diagnosed lung cancer to see if it improves 3-year progression-free survival compared with past patients.

  Recruiting West China Hospital · Chengdu, Sichuan · NCT07509333

• Autologous B7-H3 CAR T Cells in Advanced Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer

  This study tests a patient’s own B7-H3 CAR T cells to see if they can help people 18 and older whose small cell lung cancer or EPNEC has come back or hasn’t responded to prior treatment.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07509034

• Cirtuvivint plus irinotecan for relapsed small-cell lung cancer

  This trial will test whether adding cirtuvivint to irinotecan helps people with relapsed small-cell lung cancer respond better and live longer.

  Recruiting Phase 1/2 Washington University School of Medicine · St Louis, Missouri · NCT07155200

• LY4175408 for selected advanced lung, endometrial, and triple‑negative breast cancers

  This trial tests an experimental drug called LY4175408 to see if it is safe and works for people with advanced or metastatic non‑small cell or small cell lung cancer, endometrial cancer, or triple‑negative breast cancer.

  Recruiting at 24 sites Phase 1 Eli Lilly and Company · Stanford, California and 26 other locations · NCT07046923

• Higher-dose twice-daily chest radiotherapy for limited-stage small cell lung cancer

  This trial will test if higher-dose, twice-daily chest radiotherapy given with standard cisplatin and etoposide helps people with limited-stage small cell lung cancer live longer and delay recurrence.

  Recruiting at 3 sites Phase 3 Instituto de Investigación Biomédica de Salamanca · Salamanca, Salamanca and 12 other locations · NCT07015892

• Phase I testing of 225Ac-ETN029 for advanced DLL3-positive tumors

  This trial will test 225Ac-ETN029, with 111In-ETN029 used for imaging, to see if the treatment is safe, tolerable, and shows early anti-tumor activity in adults with advanced DLL3-positive neuroendocrine cancers.

  Recruiting at 8 sites Phase 1 Novartis · Iowa City, Iowa and 7 other locations · NCT07006727

• Hospital-at-Home program for patients receiving Tarlatamab

  This study is testing if a Hospital-at-Home program can help adults with advanced small cell lung cancer who are getting tarlatamab feel better while being monitored from home instead of staying in the hospital.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT06957314

• Evaluating NKT3964 for Adults with Advanced Solid Tumors

  This study is testing a new drug called NKT3964 to see if it can safely help adults with advanced solid tumors, like ovarian or triple-negative breast cancer, after other treatments have failed.

  Recruiting at 17 sites Phase 1 NiKang Therapeutics, Inc. · Little Rock, Arkansas and 20 other locations · NCT06586957

• Evaluating radiotherapy in advanced small cell lung cancer treatment

  This study is testing if adding radiotherapy to the treatment of advanced small cell lung cancer can help patients live longer without their cancer getting worse while they are already receiving chemo-immunotherapy.

  Recruiting at 2 sites Copernicus Memorial Hospital · Lublin and 1 other locations · NCT06529081

• Ongoing collection of blood and tumor samples from people with lung cancer

  Collect and store blood and tumor samples over time from adults with newly diagnosed or metastatic lung cancer to build a real-world biobank for research.

  Recruiting Nantes University Hospital · Angers and 3 other locations · NCT06481813

• Evaluating AL8326 for Small Cell Lung Cancer

  This study is testing a new pill called AL8326 to see if it can help people with small cell lung cancer who have not responded to other treatments.

  Recruiting Phase 3 Advenchen Laboratories, LLC · Changchun, Jilin · NCT06247605

• Testing a new drug for adults with advanced solid tumors

  This study is testing a new drug for adults with advanced solid tumors that haven't responded to other treatments to see if it can help them.

  Recruiting at 43 sites Phase 1 Seagen Inc. · Phoenix, Arizona and 47 other locations · NCT06131840

• Analysis and treatment options for small cell lung cancer

  This study looks at small cell lung cancer to see how its unique features can help doctors find better treatments and predict how well patients will respond to new therapies.

  Recruiting Shanghai Chest Hospital · Shanghai · NCT05945745

• Testing different doses of BI 764532 for small cell lung cancer and neuroendocrine cancers

  This study is testing different doses of a new cancer drug called BI 764532 to see if it can help adults with advanced small cell lung cancer and other neuroendocrine tumors that haven't responded to other treatments.

  Recruiting at 37 sites Phase 2 Boehringer Ingelheim · Mobile, Alabama and 58 other locations · NCT05882058

• Using Onvansertib to treat relapsed small cell lung cancer

  This study is testing a new drug called onvansertib to see if it can help people with relapsed small cell lung cancer who haven't had success with chemotherapy.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland and 1 other locations · NCT05450965

• Stereotactic radiosurgery for lung cancer that has spread to the brain

  This study is testing if a targeted radiation treatment can help people with small cell lung cancer that has spread to their brain feel better and improve their outcomes.

  Recruiting at 7 sites Phase 2 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT05419076

• Understanding lung cancer in young adults

  This study is trying to learn more about the causes of lung cancer in young adults under 45 to help improve how we screen and treat this rare condition.

  Recruiting at 2 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 3 other locations · NCT05265429

• Evaluating PC14586 for advanced solid tumors with a specific mutation

  This study is testing a new oral medication called PC14586 to see if it can help people with advanced solid tumors that have a specific mutation in the TP53 gene.

  Recruiting at 71 sites Phase 1/2 PMV Pharmaceuticals, Inc · Irvine, California and 75 other locations · NCT04585750

• Imaging small cell lung cancer with a new tracer

  This study is testing a new imaging agent to see if it can help doctors better see and identify small cell lung cancer and some related tumors in patients.

  Recruiting Phase 1/2 Memorial Sloan Kettering Cancer Center · New York, New York · NCT04199741

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Targeting immune vulnerabilities in small cell lung cancer

  A physician-scientist is undergoing a five-year training program to understand how immune cells interact with small cell lung cancer and to build skills for a future independent lab career.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11384862

• Investigating immune weaknesses in small cell lung cancer

  This study is looking at how the immune system works with small cell lung cancer to find new ways to help it fight the disease, and it's designed for patients who want to learn more about potential treatments.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11241187

• How small cell lung cancer cells switch between different states

  This research looks at how cells inside small cell lung cancer change into different types and how those changes affect treatment for people with SCLC.

  NIH research Northwestern University · Chicago, United States · NIH-11162301

• Understanding how small cell lung cancer adapts and resists treatment

  This study is looking at small cell lung cancer to understand why it grows so quickly and resists treatment, using special models from patients to find new ways to improve care for people facing this tough disease.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-10887640

Related topics

Quick answers

How many Small Cell Lung Carcinoma clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 20 countries. The most sites are in United States (13 trials), China (6 trials), France (5 trials), South Korea (5 trials), Spain (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 5, Phase 1/2: 3, Phase 2: 3, Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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