Investigating immune weaknesses in small cell lung cancer
Official title: Targeting the immunologic vulnerabilities of small cell lung carcinoma
Funded at University of Michigan at Ann Arbor · NIH-11241187 · Data updated 2026-11-12
This study is looking at how the immune system works with small cell lung cancer to find new ways to help it fight the disease, and it's designed for patients who want to learn more about potential treatments.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $191,961 |
| NIH project number | 7K08CA270077-04 |
| Project ID | NIH-11241187 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with small cell lung carcinoma who may benefit from novel immunotherapeutic approaches.
✕Less likely to help
Patients with other types of lung cancer or those who do not have small cell lung carcinoma may not receive benefits from this research.
What this research studies
This research focuses on understanding how the immune system interacts with small cell lung carcinoma, a type of lung cancer. The principal investigator, Dr. Navin R. Mahadevan, aims to explore both the internal and external factors that regulate immune responses within the tumor environment. By developing skills in antigen discovery and advanced profiling techniques, the research seeks to uncover new ways to enhance the immune system's ability to fight this cancer. This program also includes a clinical component to ensure that findings can be translated into practical applications for patient care.
Why it matters
Potential benefit: If successful, this research could lead to new immunotherapy strategies that improve treatment outcomes for patients with small cell lung carcinoma.
How similar studies have gone: Other research in tumor immunology has shown promise in enhancing immune responses against various cancers, suggesting that this approach could be beneficial.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Mahadevan, Navin — University of Michigan at Ann Arbor
- Study coordinator: Mahadevan, Navin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.