Condition

Endometrial Neoplasms clinical trials and research

• 20Clinical trials
• 13Countries

Newest Endometrial Neoplasms clinical trials

All recruiting trials (20)

• PF-08634404 plus chemotherapy in adults with advanced or recurrent pMMR endometrial cancer

  This study tests whether PF-08634404 added to standard chemotherapy helps adults with advanced or recurrent pMMR endometrial cancer more than pembrolizumab plus chemotherapy.

  Recruiting at 47 sites Phase 3 Pfizer · Jupiter, Florida and 53 other locations · NCT07578649

• POLE gene changes in high-risk endometrial cancer

  This project will test whether women with high-risk endometrial cancer have POLE gene mutations and whether those mutations change recurrence or survival.

  Recruiting Far Eastern Memorial Hospital · Banqiao District, New Taipei · NCT07114653

• LY4257496 for GRPR-positive advanced breast, colorectal, prostate, and endometrial cancer (OMNIRAY)

  This Phase 1 test tries LY4257496, with GRPR imaging using LY4257529 and sometimes standard treatments, to see if it is safe and helps people with GRPR-positive advanced breast, colorectal, prostate, or endometrial cancer.

  Recruiting at 15 sites Phase 1 Eli Lilly and Company · Duarte, California and 32 other locations · NCT07114601

• LY4175408 for selected advanced lung, endometrial, and triple‑negative breast cancers

  This trial tests an experimental drug called LY4175408 to see if it is safe and works for people with advanced or metastatic non‑small cell or small cell lung cancer, endometrial cancer, or triple‑negative breast cancer.

  Recruiting at 24 sites Phase 1 Eli Lilly and Company · Stanford, California and 26 other locations · NCT07046923

• Two-point versus four-point cervical methylene blue injections for sentinel lymph node mapping in stage I endometrial cancer

  This test checks whether using four cervical methylene blue injections instead of the usual two helps surgeons find sentinel lymph nodes in people with newly diagnosed stage I endometrial cancer who are having surgery.

  Recruiting at 2 sites Dokuz Eylul University · Ankara and 1 other locations · NCT07040657

• Testing DM002 in patients with advanced solid tumors

  This study is testing a new drug called DM002 to see if it is safe and effective for people with advanced solid tumors.

  Recruiting at 7 sites Phase 1/2 Doma Biopharmaceutical（Suzhou）Co., Ltd. · San Francisco, California and 6 other locations · NCT06751329

• Evaluating NKT3964 for Adults with Advanced Solid Tumors

  This study is testing a new drug called NKT3964 to see if it can safely help adults with advanced solid tumors, like ovarian or triple-negative breast cancer, after other treatments have failed.

  Recruiting at 17 sites Phase 1 NiKang Therapeutics, Inc. · Little Rock, Arkansas and 20 other locations · NCT06586957

• Using cadonilimab with chemotherapy and radiation for advanced endometrial cancer

  This study is testing if adding cadonilimab to chemotherapy and radiation can help people with advanced endometrial cancer live longer and feel better.

  Recruiting Phase 2 Shandong Cancer Hospital and Institute · Jinan, Shandong · NCT06532539

• Combining Carboplatin, Paclitaxel, and Pembrolizumab for Advanced Endometrial Cancer

  This study is testing a new combination of drugs for people with advanced endometrial cancer to see if it helps them live longer without their cancer getting worse.

  Recruiting at 6 sites Phase 2 Yonsei University · Kyeonggi-do and 5 other locations · NCT06502743

• Evaluating LY4170156 for advanced solid tumors

  This study is testing a new drug called LY4170156 to see if it is safe and effective for people with advanced solid tumors like ovarian and lung cancers.

  Recruiting at 24 sites Phase 1 Eli Lilly and Company · Scottsdale, Arizona and 24 other locations · NCT06400472

• Using GnRHa and Letrozole for Obese Women with Progestin-Insensitive Endometrial Cancer

  This study is testing a new treatment combining GnRH antagonist and letrozole to see if it helps obese women with a specific type of endometrial cancer that hasn't responded to standard therapy.

  Recruiting at 2 sites Phase 2/3 Fudan University · Shanghai, Shanghai Municipality and 1 other locations · NCT06379113

• Comparing robotic and traditional laparoscopic surgery for obese patients with early endometrial cancer

  This study is testing whether robotic surgery works better than traditional laparoscopic surgery for morbidly obese patients with early endometrial cancer.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT05974995

• Fertility-sparing therapy for early-stage endometrial cancer

  This study is testing a new treatment approach for women with early-stage endometrial cancer to see if it can help them keep their ability to have children while also checking how well it works over time.

  Recruiting Peking University People's Hospital · Beijing, Beijing Municipality · NCT05945407

• Using Nivolumab for Treating Resectable Mismatch Repair Deficient Endometrial Cancer

  This study is testing if the drug Nivolumab can help women with a specific type of endometrial cancer that can be surgically removed, to see if it leads to better treatment outcomes.

  Recruiting Phase 2 Yonsei University · Seoul · NCT05795244

• Using atezolizumab to treat cancers with high mutation rates or specific genetic deficiencies

  This study is testing if atezolizumab can help treat adults and kids with certain types of cancers that have a lot of genetic changes or specific genetic issues.

  Recruiting at 23 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT05770102

• Comparing uterine manipulator use in endometrial cancer surgery

  This study is testing if using a uterine manipulator during surgery for endometrial cancer helps patients do better in the long run compared to surgery without it.

  Recruiting at 3 sites Universita di Verona · Cuneo, Italy and 2 other locations · NCT05687084

• Combining GnRHa and Letrozole for Non-obese Patients with Endometrial Cancer

  This study is testing if a combination of GnRHa and letrozole can help non-obese patients with early-stage endometrial cancer keep their fertility when standard treatments haven't worked.

  Recruiting at 2 sites Phase 2/3 Fudan University · Shanghai, Shanghai Municipality and 1 other locations · NCT05316935

• National registry for ovarian and endometrial cancer patients

  This study is setting up a national registry to track information about patients with advanced ovarian and endometrial cancer in Germany to see how they respond to different treatments over time.

  Recruiting iOMEDICO AG · Multiple Locations · NCT05129969

• Examining the impact of small-volume lymph node disease in endometrial and cervical cancer

  This study is trying to see how small amounts of cancer in lymph nodes affect treatment choices and outcomes for people with early-stage endometrial and cervical cancer.

  Recruiting Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Milan · NCT04403867

• Early diagnosis of ovarian and endometrial cancer using genomic testing

  This study is testing a new DNA test to see if it can help catch ovarian and endometrial cancers early by looking for specific changes in samples taken from the cervix and uterus.

  Recruiting McGill University · Montreal, Quebec · NCT02288676

Related topics

Quick answers

How many Endometrial Neoplasms clinical trials are recruiting right now?

20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in China (7 trials), United States (6 trials), South Korea (5 trials), Italy (4 trials), Japan (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 4, Phase 2: 3, Phase 2/3: 3, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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