Understanding lung cancer in young adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research focuses on individuals diagnosed with lung cancer at age 45 or younger, aiming to gather insights into the causes and risk factors associated with this rare condition. The study will enroll approximately 500 participants and will involve collecting medical records, questionnaires, blood or saliva samples, and optional tumor tissue samples. By examining genetic changes and other factors, the study seeks to improve screening and treatment options for young lung cancer patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 45 and under at lung cancer diagnosis
* Pathologically confirmed bronchogenic lung carcinoma (NSCLC or SCLC of any stage) at any treatment time point
* Provision of written informed consent
* Willingness to undergo no more than two (2) peripheral blood draws in a four (4) week period, with no more than 50 ml peripheral blood collected over eight (8) weeks
* Individuals under age 18 are eligible for study if they meet defined criteria; in addition, consent for participation must be given by a legal guardian or parent

Exclusion Criteria:

* Individuals who decline to sign consent
* Individuals who are unable to give consent or assent and are without a designated healthcare proxy
* Compromise of patient diagnosis or staging if tissue is used for research

Where it's running

• Massachusetts General Hospital
  Boston, Massachusetts, United States Recruiting
• Dana-Farber Cancer Institute
  Boston, Massachusetts, United States Recruiting
• Beth Israel Deaconess Medical Center
  Boston, Massachusetts, United States Not yet recruiting
• Brigham and Women's Hospital
  Boston, Massachusetts, United States Not yet recruiting

Study contacts

• Principal investigator: Pasi A Janne, MD, PhD — Dana-Farber Cancer Institute
• Study coordinator: Jaclyn LoPiccolo, MD, PhD
• Email: Jaclyn_LoPiccolo@dfci.harvard.edu
• Phone: 857-215-8041

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.