Condition

Sickle Cell Disease (SCD) clinical trials and research

• 8Clinical trials
• 5Countries

Newest Sickle Cell Disease (SCD) clinical trials

All recruiting trials (8)

• Sickle cell disease registry at Ain Shams University

  This project creates an Ain Shams University registry of children and young people with sickle cell disease to track their health over time without providing a treatment.

  Recruiting Ain Shams University · Cairo and 1 other locations · NCT07800247

• Point-of-care newborn SCD screening and early care in Côte d'Ivoire

  This trial tests whether using a Gazelle-Multispectral point-of-care test at birth plus early, comprehensive SCD care can reduce illnesses and deaths for babies with SCD in the first years of life.

  Recruiting Phase 4 Swiss Tropical & Public Health Institute · Abidjan and 1 other locations · NCT07488520

• Sickle Cell Kidney Sample Bank

  This project will collect blood and urine from adults with sickle cell disease or sickle cell trait to see if linked samples and medical records can help researchers learn how kidney disease starts and progresses.

  Recruiting at 2 sites University of Texas Southwestern Medical Center · Dallas, Texas and 1 other locations · NCT07064174

• Comparing stem cell transplantation to disease-modifying therapy for children with sickle cell disease

  This study is trying to see how well stem cell transplants work compared to other treatments for children with sickle cell disease over three years.

  Recruiting at 16 sites University of Rochester · Birmingham, Alabama and 36 other locations · NCT06941389

• Examining megakaryocytes in patients with sickle cell disease

  This study looks at how certain blood cells called megakaryocytes behave in people with sickle cell disease to see if they play a role in the complications of the illness.

  Recruiting University Hospital, Toulouse · Toulouse, France · NCT06887907

• Adjusting hydroxyurea dose using pharmacokinetics in children with sickle cell disease

  This study tests whether using pharmacokinetic testing to guide hydroxyurea dosing helps kids with sickle cell disease reach the maximum tolerated dose faster than standard blood testing alone.

  Recruiting Phase 2/3 St. Justine's Hospital · Montreal, Quebec · NCT06761560

• Depo-Provera (depot medroxyprogesterone acetate) for pain and biomarker changes in women with sickle cell disease

  This study will test whether an injectable birth control (Depo-Provera) can reduce pain in adult women with sickle cell disease.

  Recruiting Phase 4 University of Pennsylvania · Atlanta, Georgia and 1 other locations · NCT06665997

• Global reflexology for pain relief in children with sickle cell disease

  Try global reflexology to see if it reduces pain in children under 18 hospitalized for sickle cell vaso-occlusive crises.

  Recruiting Hospices Civils de Lyon · Bron · NCT06619197

Related topics

Quick answers

How many Sickle Cell Disease (SCD) clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (3 trials), France (2 trials), Canada (2 trials), Côte d’Ivoire (1 trial), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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