Global reflexology for pain relief in children with sickle cell disease
Official title: Exploratory Study on Global Reflexology Proposed in the Management of Pain in Children With Sickle Cell Disease in Vaso-occlusive Crisis
Run by Hospices Civils de Lyon · NCT06619197 · Data updated 2026-11-12
Try global reflexology to see if it reduces pain in children under 18 hospitalized for sickle cell vaso-occlusive crises.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | Any age to 18 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Bron) |
| Status | Recruiting |
| Started | June 30, 2025 |
| Main results expected | July 30, 2027 |
| Study ends | July 30, 2027 |
| Registry record updated | July 8, 2025 |
| Trial ID | NCT06619197 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children under 18 with sickle cell disease who are hospitalized in the UHCD or USC units of Hôpital Femme Mère Enfant (Hospices Civils de Lyon) for management of a vaso-occlusive crisis, with parental consent and patient assent as appropriate.
✕Probably not a fit
Patients receiving patient-controlled or nurse-controlled analgesia, adults, or those not hospitalized in the specified units are not eligible and therefore unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional exploratory program applies global reflexology to children with sickle cell disease who are admitted for vaso-occlusive crises. Trained childcare staff will deliver reflexology sessions during hospitalization with parental consent and the child's assent when appropriate. The protocol excludes patients on patient-controlled or nurse-controlled analgesia and focuses on those treated in the UHCD or USC units. Pain and clinical course during the hospital stay will be monitored to detect any change associated with the reflexology sessions.
Why it matters
Potential benefit: If effective, this could reduce acute pain during vaso-occlusive crises and provide a simple non-drug technique usable by paramedical staff.
How similar studies have gone: A small 2013 case series of 12 sickle cell patients reported pain reduction in eight patients after reflexology, but larger controlled trials confirming benefit are lacking.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient under 18 years of age * Patient suffering from sickle cell disease * Patient hospitalized in the UHCD or USC unit of the Women\'s Mother and Child Hospital of the Hospices Civils de Lyon for the management of a CVO * Informed consent signed by at least one holder of parental authority * Collection of the patient\'s assent as soon as his age allows it. Exclusion Criteria: * Patient with PCA (Patient Controlled Analgesia) * Patient with NCA (Nurse Controlled Analgesia) * Patient not affiliated to a social security scheme or beneficiaries of a similar scheme.
Where it's running
-
Hôpital Femme Mère Enfant
Bron, France Recruiting
Study contacts
- Principal investigator: Collot Sophie — Hospices Civils de Lyon
- Study coordinator: COLLOT Sophie
- Email: sophie.collot@chu-lyon.fr
- Phone: 0033472115165
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Sickle cell disease registry at Ain Shams University
This project creates an Ain Shams University registry of children and young people with sickle cell disease to track their health over time without providing a treatment.
-
Point-of-care newborn SCD screening and early care in Côte d'Ivoire
This trial tests whether using a Gazelle-Multispectral point-of-care test at birth plus early, comprehensive SCD care can reduce illnesses and deaths for babies with SCD in the first years of life.
-
Sickle Cell Kidney Sample Bank
This project will collect blood and urine from adults with sickle cell disease or sickle cell trait to see if linked samples and medical records can help researchers learn how kidney disease starts and progresses.
-
Comparing stem cell transplantation to disease-modifying therapy for children with sickle cell disease
This study is trying to see how well stem cell transplants work compared to other treatments for children with sickle cell disease over three years.
-
Examining megakaryocytes in patients with sickle cell disease
This study looks at how certain blood cells called megakaryocytes behave in people with sickle cell disease to see if they play a role in the complications of the illness.
-
Adjusting hydroxyurea dose using pharmacokinetics in children with sickle cell disease
This study tests whether using pharmacokinetic testing to guide hydroxyurea dosing helps kids with sickle cell disease reach the maximum tolerated dose faster than standard blood testing alone.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.