Condition

Vaso-Occlusive Pain Episode in Sickle Cell Disease clinical trials and research

• 4Clinical trials
• 3Countries

Newest Vaso-Occlusive Pain Episode in Sickle Cell Disease clinical trials

All recruiting trials (4)

• Low-dose ketamine for sickle cell vaso-occlusive pain in children and young adults

  This trial will test whether adding a low (sub-dissociative) dose ketamine infusion to usual IV opioid pain medicine helps children and young adults (ages 5–20) with sickle cell disease have better pain relief and remain safe during a vaso-occlusive episode.

  Recruiting Phase 2 Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, California · NCT07369024

• Lidocaine to Help Spare Opioids During Vaso-occlusive Crises in Sickle Cell Disease

  This study tests whether adding lidocaine to standard pain care during a vaso-occlusive crisis can reduce the total opioid use in adults with sickle cell disease.

  Recruiting at 12 sites Phase 3 Nantes University Hospital · Bordeaux and 11 other locations · NCT07274254

• Depo-Provera (depot medroxyprogesterone acetate) for pain and biomarker changes in women with sickle cell disease

  This study will test whether an injectable birth control (Depo-Provera) can reduce pain in adult women with sickle cell disease.

  Recruiting Phase 4 University of Pennsylvania · Atlanta, Georgia and 1 other locations · NCT06665997

• Using virtual reality to help manage pain in sickle cell disease patients

  This study is testing if using virtual reality can help adults with sickle cell disease feel less pain during painful episodes.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06184126

Related topics

Quick answers

How many Vaso-Occlusive Pain Episode in Sickle Cell Disease clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (3 trials), France (1 trial), Guadeloupe (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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