Condition
Severe Hypoglycemia clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Severe Hypoglycemia clinical trials that are recruiting, at sites in 12 countries (most in United States (2), China (1), Canada (1)). By phase: Phase 1/2 (2), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 12Countries
Newest Severe Hypoglycemia clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| E-islet 01 therapy for people with long-standing Type 1 diabetes and impaired hypoglycemia awareness | Phase 1/2 | Shanghai, Shanghai Municipality | Recruiting | Aug 17, 2025 |
| Study of how children's bodies respond to low blood sugar in type 1 diabetes | — | Brussels, Woluwe-saint-lambert | Recruiting | Jan 13, 2025 |
| Investigating the safety and effectiveness of porcine pancreatic cells in patients with Type 1 diabetes | Phase 1/2 | Chicago, Illinois | Recruiting | Aug 28, 2024 |
| Evaluating VX-880 for Type 1 Diabetes with Severe Hypoglycemia | Phase 3 | Duarte, California and 28 other locations | Recruiting | Mar 8, 2021 |
All recruiting trials (4)
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E-islet 01 therapy for people with long-standing Type 1 diabetes and impaired hypoglycemia awareness
This trial will test whether E-islet 01, an allogeneic human islet cell therapy, is safe and helps reduce severe or unrecognized low blood sugars in people with Type 1 diabetes of more than five years’ duration.
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Study of how children's bodies respond to low blood sugar in type 1 diabetes
This study is trying to see how children's bodies with type 1 diabetes react to low blood sugar to help improve their management of hypoglycemia.
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Investigating the safety and effectiveness of porcine pancreatic cells in patients with Type 1 diabetes
This study is testing if using pig pancreas cells can help adults with tough-to-manage Type 1 diabetes feel better and avoid dangerous low blood sugar episodes.
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Evaluating VX-880 for Type 1 Diabetes with Severe Hypoglycemia
This study is testing if a new treatment called VX-880 can help people with Type 1 diabetes who have trouble sensing low blood sugar and have had severe low blood sugar episodes.
Related topics
Quick answers
How many Severe Hypoglycemia clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 12 countries. The most sites are in United States (2 trials), China (1 trial), Canada (1 trial), France (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.