Condition

Post-Dural Puncture Headache clinical trials and research

• 8Clinical trials
• 1New in 30 days
• 7Countries

Newest Post-Dural Puncture Headache clinical trials

All recruiting trials (8)

• Epidural hydroxyethyl starch to prevent post-dural puncture headache in parturients

  This study tests whether filling the epidural space with hydroxyethyl starch can help prevent post-dural puncture headaches in women who had an accidental dural puncture during epidural anesthesia for labor or cesarean delivery.

  Recruiting Peking University First Hospital · Beijing, Beijing Municipality and 3 other locations · NCT07914790

• Predicting Post-Dural Puncture Headache After Spinal Anesthesia in Cesarean Deliveries

  This study tests whether changes in optic nerve sheath diameter after spinal anesthesia can predict who will develop a post-dural puncture headache in pregnant women having an elective cesarean.

  Recruiting Ordu University · Ordu, Altinordu · NCT07729449

• Treating post-dural puncture headache with theophylline, sumatriptan, or gabapentin

  This trial will try theophylline, sumatriptan, and gabapentin to see which best relieves moderate-to-severe post-dural puncture headache in adults aged 21–50.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07515456

• Sphenopalatine ganglion block versus epidural blood patch for post-dural puncture headache

  This test compares a sphenopalatine ganglion block and an epidural blood patch to see which relieves post-dural puncture headaches better in adults whose pain hasn't improved after 24 hours of usual treatment.

  Recruiting Phase 3 University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT07354464

• Nebulized neostigmine/atropine versus nebulized lidocaine for post-dural puncture headache after cesarean delivery

  This trial tests whether inhaled (nebulized) neostigmine with atropine relieves post-dural puncture headache better than inhaled lidocaine in women who develop headache after spinal anesthesia for elective cesarean delivery.

  Recruiting Early Phase 1 Minia University · Minya · NCT06824025

• Exploring causes and treatments for postural puncture headache

  This study is trying to understand what causes post-dural puncture headaches and how treatments like epidural blood patches can help people who get them after a lumbar puncture.

  Recruiting Umeå University · Umeå, Västerbotten County · NCT06253754

• Impact of altitude on headaches after cesarean delivery

  This study is testing how living at different altitudes affects the headaches that women experience after having a cesarean delivery with spinal anesthesia.

  Recruiting at 2 sites B.P. Koirala Institute of Health Sciences · Jumla, Karnali and 1 other locations · NCT05804448

• Using Neostigmine and Glycopyrrolate to Treat Headaches After Dural Puncture

  This study tests if using Neostigmine and Glycopyrrolate can help new mothers with headaches after an accidental dural puncture during childbirth, reducing the need for a blood patch treatment.

  Recruiting Phase 2 Mayo Clinic · Rochester, Minnesota · NCT05116930

Quick answers

How many Post-Dural Puncture Headache clinical trials are recruiting right now?

8, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in Egypt (2 trials), France (1 trial), Nepal (1 trial), Turkey (Türkiye) (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Early Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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