Predicting Post-Dural Puncture Headache After Spinal Anesthesia in Cesarean Deliveries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates whether ultrasound measurements of optic nerve sheath diameter (ONSD) after spinal anesthesia correlate with the onset of post-dural puncture headache (PDPH) in women at term undergoing cesarean delivery. It also explores whether monitoring cerebral oxygenation with near-infrared spectroscopy (NIRS) during spinal-induced hypotension provides additional predictive value for PDPH. The goal is to establish a potential ONSD cutoff to foresee PDPH and to assess the clinical relevance of NIRS-derived cerebral desaturation in this context. Eligible participants are 18-40 years old, ASA II-III, past 37 weeks gestation, undergoing elective cesarean delivery, and able to consent. The study is conducted at Ordu University with the lead sponsor listed as Ordu University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-40 years,
* American Society of Anesthesiologists (ASA) physical status classification of II or III,
* Beyond 37 weeks of gestation,
* Elective cesarean delivery,
* Provided written informed consent

Exclusion Criteria:

* Patients undergoing emergency cesarean delivery
* Presence of preoperative anxiety \[State-Trait Anxiety Inventory (STAI) - I\] score \> 30)
* Presence of preoperative anemia (Hemoglobin \< 11 g/dL),
* History of hypertension, gestational hypertension, hyperthyroidism, or preeclampsia/eclampsia,
* Presence of fetal and/or placental anomalies,
* Known neurological, psychiatric, cardiovascular, or muscular diseases,
* Chronic headache,
* Active ocular disease or optic nerve damage,
* Allergies to local anesthetics or other medications,
* Requirement for intraoperative general anesthesia,
* Presence of contraindications to neuraxial anesthesia or conversion to intraoperative general anesthesia,
* Multiple puncture attempts during spinal anesthesia administration,
* Development of postpartum hemorrhage.

Where it's running

• Name: Ordu University Training and Research Hospital
  Ordu, Altinordu, Turkey (Türkiye) Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.