Condition
POEMS Syndrome clinical trials and research
As of November 12, 2026, Find a Trial lists 4 POEMS Syndrome clinical trials that are recruiting, at sites in 2 countries (most in China (3), Italy (1)). By phase: Phase 2 (2), Early Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest POEMS Syndrome clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| KCD Regimen for Newly Diagnosed POEMS Syndrome | Phase 2 | Shanghai | Recruiting | Jun 17, 2026 |
| How the IGLV1-44 light chain causes AL amyloidosis and POEMS | — | Pavia | Recruiting | Mar 4, 2026 |
| BCMA/CD3 bispecific antibody therapy for POEMS syndrome | Phase 2 | Tianjin | Recruiting | Aug 11, 2025 |
| Using CT103A cells to treat autoimmune diseases of the nervous system | Early Phase 1 | Wuhan, Hubei | Recruiting | Sep 23, 2020 |
All recruiting trials (4)
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KCD Regimen for Newly Diagnosed POEMS Syndrome
The study tests whether the KCD regimen (carfilzomib, cyclophosphamide, and dexamethasone) is safe and effective in adults newly diagnosed with POEMS syndrome.
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How the IGLV1-44 light chain causes AL amyloidosis and POEMS
This project tests whether specific IGLV1-44 light‑chain sequences drive AL amyloidosis and POEMS and whether nanobodies can recognize and stabilize those light chains in adults with AL amyloidosis, POEMS, or multiple myeloma.
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BCMA/CD3 bispecific antibody therapy for POEMS syndrome
This trial tests CM336, a BCMA/CD3 bispecific antibody, in adults with POEMS syndrome to see if it is safe and can help the condition.
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Using CT103A cells to treat autoimmune diseases of the nervous system
This study is testing if a new treatment using CT103A cells can help people with certain autoimmune diseases affecting the nervous system feel better.
Related topics
Quick answers
How many POEMS Syndrome clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (3 trials), Italy (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.