Condition

Overweight , Obesity clinical trials and research

• 19Clinical trials
• 12NIH research projects
• 2New in 30 days
• 10Countries

Newest Overweight , Obesity clinical trials

All recruiting trials (19)

• Semaglutide on body composition in adults with type 1 diabetes and overweight/obesity

  This study tests whether weekly semaglutide changes body composition in adults with type 1 diabetes who are overweight or obese, compared with a placebo over 24 weeks.

  Recruiting Phase 2/3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07891156

• UBT37034 Injection safety study in adults with overweight or obesity

  This study tests different doses of UBT37034 injections to see if they are safe and tolerable in adults who are overweight or have obesity.

  Recruiting Phase 1 The United Bio-Technology (Hengqin) Co., Ltd. · Changsha, Hunan · NCT07873645

• Two-Week Stair-Climbing “Exercise Snacks” to Test Metabolic Health

  In adults with overweight or obesity who don’t exercise regularly, a two-week program of short stair climbs throughout the day will be tested to see if it improves metabolic health and fitness.

  Recruiting St. Louis University · St Louis, Missouri · NCT07849439

• Tegileridine for pain after bariatric surgery

  This phase 3 trial tests tegileridine vs standard opioid medicine to see if it provides good pain relief after bariatric surgery while considering sleep apnea status.

  Recruiting Phase 3 The First Hospital of Jilin University · Changchun, Jilin · NCT07844512

• Weight-loss maintenance with ALV-100 after prior weight loss

  This study tests whether ALV-100 helps adults who already lost weight with incretin therapies keep the weight off, compared with placebo.

  Recruiting at 20 sites Phase 2 Alveus Therapeutics, Inc. · Birmingham, Alabama and 19 other locations · NCT07837973

• Dietary guidelines-based eating plan to reduce menopausal symptoms in overweight and obese women

  A randomized trial will test whether following healthy eating guidance from Brazil’s dietary guidelines can lessen menopausal symptoms in women who are overweight or obese.

  Recruiting Federal University of Health Science of Porto Alegre · Porto Alegre, Rio Grande do Sul · NCT07822230

• MWN105 injection in overweight or obese adults you may join

  This early-phase trial tests whether MWN105 is safe and tolerable in overweight or obese adults in China, using a placebo comparison.

  Recruiting Phase 1 Shanghai Minwei Biotechnology Co., Ltd · Kunming, Yunnan · NCT07803809

• 30-30-30 weight loss plan tested online with protein, fiber, and exercise

  This online weight loss program tests whether the 30-30-30 plan helps people lose weight better than an online program alone for adults aged 18 to 69 with BMI 27–45.

  Recruiting at 3 sites Midwest Center for Metabolic and Cardiovascular Research · Addison, Illinois and 2 other locations · NCT07789769

• Probiotic mix to see if it boosts fullness in adults who are overweight or have obesity

  A probiotic supplement is being tested in adults aged 20-70 who are overweight or have obesity to see if it makes them feel fuller and changes gut bacteria harder after 16 weeks, compared with a placebo.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07715955

• Combining 10-day Fasting with Fibre to Boost Gut Health

  This study tests whether adding dietary fibre to a 10-day fast improves gut microbiome function and metabolic health in adults with overweight or obesity.

  Recruiting Buchinger Wilhelmi Development & Holding GmbH · Überlingen, Baden-Wurttemberg · NCT07691736

• Natural history and prognostic factors of therapeutic response in sub-phenotypes of obesity

  This study follows adults with obesity or overweight to see how different subtypes respond to obesity therapies using data and machine learning.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Bologna · NCT07666425

• SucroMet: Does table sugar or sucralose affect glucose control in adults of different weights?

  This trial tests whether eating sucrose or taking sucralose at low or high doses for several weeks changes glucose regulation in adults aged 18–65 with normal weight to obesity.

  Recruiting Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud · Málaga, Malaga · NCT07656298

• IBIO-600: testing a single dose in adults who are overweight or obese

  A single dose of IBIO-600 is being tested in adults with overweight or obesity to see if it is safe, tolerable, and shows potential effects on body composition compared with placebo.

  Recruiting Phase 1 iBio, Inc. · Bayswater, Victoria · NCT07487376

• High‑phenolic versus low‑phenolic extra virgin olive oil for metabolic health in adults with central obesity

  This trial will see if daily high‑phenolic extra virgin olive oil for eight weeks improves metabolic markers in adults with overweight or central obesity who have at least one metabolic abnormality.

  Recruiting University of Peloponnese · Kalamata · NCT07445503

• Exercise timing for people with prediabetes and overweight/obesity

  This study tests whether doing a single exercise session in the morning or in the evening helps control blood sugar better in adults with prediabetes who are overweight or obese.

  Recruiting German Diabetes Center · Düsseldorf · NCT07389005

• Smartwatch-based program to improve heart health in adults with overweight and cardiometabolic risk

  This project will test whether a smartwatch-led exercise, diet, and coaching program can help adults who are overweight or obese with prehypertension, prediabetes, or borderline high cholesterol improve their cardiovascular health.

  Recruiting at 3 sites Beijing Anzhen Hospital · Beijing, Beijing Municipality and 2 other locations · NCT07372729

• Outcomes for children with obesity in the Get Up & Go healthy lifestyle program

  This project will try whether the Get Up & Go family healthy lifestyle program helps children ages 6–14 with BMI at or above the 85th percentile improve health and activity measures compared with a waitlisted group.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT07342855

• Weight loss with AKM Lab-01 probiotic versus placebo

  This study tests whether daily AKM Lab-01 can help people who are overweight or obese lose weight compared with a placebo over 3 months.

  Recruiting Moon (Guangzhou) Biotechnology Co., Ltd. · Guangzhou, Guangdong · NCT07331974

• Asiaticoside treatment for adults with overweight or obesity

  This study will try oral asiaticoside tablets to see if they help adults with overweight or obesity lose weight and improve related metabolic measures.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07241533

NIH-funded research (12)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Telehealth Parent-Only Treatment for Kids with Autism and Overweight/Obesity

  A telehealth program helps parents of children with autism and overweight/obesity lose weight and improve behaviors, using parent-focused sessions delivered remotely.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11374887

• Understanding how phthalate exposure before birth affects childhood weight and if certain diets can help

  This project explores how exposure to common chemicals before birth might affect a child's weight and if healthy eating habits can offer protection.

  NIH research University of Delaware · Newark, UNITED STATES · NIH-11129921

• Telehealth Support for Parents of Children with Autism and Weight Concerns

  This project helps parents of children with autism spectrum disorder who are also overweight or obese learn strategies to support their child's health through online sessions.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11115854

• Effects of sedentary time on heart function in youth with overweight or obesity

  This study is looking at how sitting too much might impact the heart's health in young people who are overweight or obese, to help find ways to keep their hearts healthier.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11001243

• Helping parents promote healthy eating and exercise in pediatric cancer survivors with obesity

  This study is helping families of kids aged 5-11 who have survived cancer and are dealing with being overweight or obese by encouraging parents to promote healthy eating and exercise, making it easier for everyone to adopt better habits together.

  NIH research University of South Florida · Tampa, United States · NIH-10993174

• How prenatal exposure to phthalates affects childhood obesity and dietary strategies to protect against it

  This study is looking at how being exposed to certain chemicals during pregnancy might affect a child's weight as they grow up, and it will also explore ways to help reduce any weight gain linked to these chemicals through diet.

  NIH research University of Delaware · Newark, UNITED STATES · NIH-10975064

• Effects of chemical exposure on weight loss in Hispanic children

  This study is looking at how certain chemicals in our environment might affect weight loss in overweight and obese Hispanic kids who are part of a community weight loss program, by checking their weight and health before and after a 10-week program.

  NIH research George Mason University · Fairfax, United States · NIH-10938574

• Understanding eating control issues in Black adolescents with obesity and the impact of social factors.

  This study is looking at how social situations and experiences of racial discrimination impact eating habits in Black teens who are overweight or obese, and it aims to understand their feelings of losing control over eating by talking to them and gathering real-time information about their daily lives.

  NIH research University of Connecticut Storrs · Storrs-Mansfield, United States · NIH-10916380

• Telehealth treatment for parents of children with autism and obesity

  This study is testing a new online program to help parents of children with autism who are also struggling with being overweight, giving them helpful tips to manage their child's weight from the comfort of home.

  NIH research University of California, San Diego · La Jolla, United States · NIH-10862879

• Understanding how executive functioning affects weight and eating behaviors in children with obesity

  This study is looking at how kids and teens who are overweight or obese can improve their eating habits and weight by understanding how their thinking skills, like decision-making and self-control, affect their eating choices.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10823240

• Effects of chemical exposure on weight loss in Hispanic children

  This study is looking at how certain chemicals in our environment might affect weight loss in overweight and obese Hispanic kids who are part of a community weight loss program, by checking their weight and health before and after a 10-week program.

  NIH research George Mason University · Fairfax, United States · NIH-10724050

• How sleep affects eating behaviors in children with overweight or obesity

  This study looks at how sleep affects eating habits in kids who are overweight or obese, hoping to find ways to help them make healthier choices and feel better overall.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10610402

Related topics

Quick answers

How many Overweight , Obesity clinical trials are recruiting right now?

19, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in China (6 trials), United States (4 trials), Germany (2 trials), Australia (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 2: 1, Phase 2/3: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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