Condition

Medulloblastoma Recurrent clinical trials and research

• 9Clinical trials
• 8Countries

Newest Medulloblastoma Recurrent clinical trials

All recruiting trials (9)

• Neuro-navigation-guided focused ultrasound with nivolumab for relapsed or progressive high-grade brain tumors in children

  This study tests whether using focused ultrasound to open the blood-brain barrier and give nivolumab is safe and feasible for kids with relapsed or progressive DMG/DIPG or other high-grade brain tumors.

  Recruiting Phase 1 Children's National Research Institute · Washington D.C., District of Columbia · NCT07664176

• B7-H3 CAR T cells for recurrent brain tumors in kids and young adults

  This early-phase trial tests a personalized CAR T-cell therapy called B7-H3 CAR T for children and young adults with recurrent or progressive brain tumors.

  Recruiting at 2 sites Phase 1 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT07390539

• Liothyronine with BIT chemotherapy for relapsed medulloblastoma in kids and young adults

  This study tests Liothyronine (L-T3) with a BIT chemotherapy regimen in children and young adults whose medulloblastoma has come back or progressed after standard treatment.

  Recruiting at 2 sites Phase 1/2 University of California, San Francisco · San Francisco, California and 2 other locations · NCT07346157

• Registry for relapsed or progressive SHH medulloblastoma with U1 mutation

  This registry collects medical records and biological samples from people aged 3–50 with relapsed or progressive SHH medulloblastoma to test for U1 mutations and create a biobank for research.

  Recruiting at 2 sites Baylor College of Medicine · Houston, Texas and 1 other locations · NCT07242963

• TP53 gene therapy (SGT-53) with nivolumab and focused radiation for children with recurrent brain tumors

  This study tests a TP53 gene therapy called SGT-53 combined with the immune drug nivolumab and focused radiation in children whose brain tumors have come back, grown, or not responded to prior treatment.

  Recruiting Early Phase 1 Children's National Research Institute · Washington D.C., District of Columbia · NCT07017816

• Combining Lutathera® and Olaparib for treating recurrent solid tumors in children and adolescents

  This study is testing if combining Lutathera® with olaparib can help children and teenagers with hard-to-treat solid tumors that have certain receptors.

  Recruiting Phase 1/2 Fundación de investigación HM · Boadilla del Monte, Madrid · NCT06607692

• Personalized treatment for children and young adults with relapsed brain tumors

  This study is testing personalized treatment plans for children and young adults with relapsed brain tumors to see if using real-time drug screening and genetic information can help them get the best and safest therapies.

  Recruiting at 9 sites University of California, San Francisco · Los Angeles, California and 8 other locations · NCT05057702

• Using a virus therapy to treat recurrent cerebellar brain tumors in children

  This study is testing a new virus treatment for children with recurring brain tumors to see if it can help them get better when combined with a low dose of radiation.

  Recruiting at 3 sites Phase 1 M.D. Anderson Cancer Center · Birmingham, Alabama and 2 other locations · NCT03911388

• New treatment for children with recurrent brain tumors

  This study is testing a new treatment combining an intravenous drug with five oral medications to see if it can help children with recurring brain tumors live longer and feel better.

  Recruiting at 18 sites Phase 2 Medical University of Vienna · Chicago, Illinois and 21 other locations · NCT01356290

Related topics

Quick answers

How many Medulloblastoma Recurrent clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (8 trials), Spain (2 trials), Austria (1 trial), Czechia (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 1/2: 2, Early Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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