Condition

Pineoblastoma clinical trials and research

• 6Clinical trials
• 2Countries

Newest Pineoblastoma clinical trials

All recruiting trials (6)

• B7-H3 CAR T cells for recurrent brain tumors in kids and young adults

  This early-phase trial tests a personalized CAR T-cell therapy called B7-H3 CAR T for children and young adults with recurrent or progressive brain tumors.

  Recruiting at 2 sites Phase 1 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT07390539

• GPC2-targeted CAR T cell therapy for relapsed or refractory medulloblastoma in children and young adults

  This trial will test whether autologous GPC2-targeted CAR T cells delivered into the brain ventricle are safe and active for children and young adults with relapsed or refractory medulloblastoma or similar CNS embryonal tumors.

  Recruiting Phase 1 Stanford University · Palo Alto, California · NCT07087002

• TP53 gene therapy (SGT-53) with nivolumab and focused radiation for children with recurrent brain tumors

  This study tests a TP53 gene therapy called SGT-53 combined with the immune drug nivolumab and focused radiation in children whose brain tumors have come back, grown, or not responded to prior treatment.

  Recruiting Early Phase 1 Children's National Research Institute · Washington D.C., District of Columbia · NCT07017816

• Intrathecal topotecan with maintenance chemotherapy after consolidation for high‑risk embryonal brain tumors in children under 6

  This study will test whether monthly intrathecal topotecan plus a year of oral maintenance chemotherapy after high‑dose consolidation is feasible and tolerable for children under 6 with high‑risk embryonal brain tumors.

  Recruiting at 12 sites Early Phase 1 C17 Council · Calgary, Alberta and 12 other locations · NCT06942039

• Immunotherapy using personalized T cells for pediatric brain tumors

  This study is testing a new treatment using personalized immune cells to help young children with certain brain tumors that haven't completely gone away after standard treatment.

  Recruiting Phase 1 Children's National Research Institute · Washington D.C., District of Columbia · NCT06193759

• Registry for rare lung tumors and DICER1-related conditions

  This study is collecting information about rare lung tumors in children, like pleuropulmonary blastoma, to help doctors understand how these conditions develop and how to treat them better.

  Recruiting Children's Hospitals and Clinics of Minnesota · Minneapolis, Minnesota · NCT03382158

Related topics

Quick answers

How many Pineoblastoma clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (5 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Early Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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