Condition

Malignant Pleural Effusion clinical trials and research

• 7Clinical trials
• 4Countries

Newest Malignant Pleural Effusion clinical trials

All recruiting trials (7)

• Fast TIL therapy for cancers that have spread to the pleura, including mesothelioma

  This study will try a patient's own pleural T cells grown briefly in the lab and given into the chest with local IL-2 to treat people with malignant pleural effusions or pleural mesothelioma who have exhausted standard treatments.

  Recruiting Phase 1 Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Pittsburgh, Pennsylvania · NCT07443020

• Fast TIL therapy for cancers that have spread to the pleura

  This treatment will try a patient's own pleural T cells, grown quickly in the lab and given into the chest with local IL-2, for adults whose cancer has spread to the pleura or for pleural mesothelioma.

  Recruiting Phase 1 Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Pittsburgh, Pennsylvania · NCT07192900

• Does turning patients during doxycycline pleurodesis improve success and comfort for malignant pleural effusion?

  We will test whether turning people during doxycycline pleurodesis helps seal cancer-related pleural fluid and improves comfort.

  Recruiting Ain Shams University · Cairo · NCT07147270

• MT027 treatment for patients with pleural malignant tumors

  This study is testing a new treatment called MT027 for patients with pleural malignant tumors to see if it's safe and how well it works after they have already received standard treatment.

  Recruiting Phase 1 Suzhou Maximum Bio-tech Co., Ltd. · Beijing · NCT06726564

• Infusing tocilizumab into chest and abdominal cavities for advanced cancer patients

  This study is testing if giving tocilizumab directly into the chest and abdomen can help advanced cancer patients with fluid buildup feel better and respond to treatment.

  Recruiting Phase 1 Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Pittsburgh, Pennsylvania · NCT06016179

• Registry for pleural fluid samples from lung cancer and infection patients

  This study is collecting fluid samples from patients with lung cancer or lung infections to see if they can help create better tests and treatments for these conditions.

  Recruiting UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT05620329

• Oncodrivers in Pleural Fluid for NSCLC with Malignant Pleural Effusion

  This study tests whether PD-L1, ALK, and EGFR can be detected in pleural fluid from NSCLC patients with malignant effusion to see how common these oncodriver markers are.

  Recruiting Naestved Hospital · Næstved, Region Sjælland · NCT04806412

Related topics

Quick answers

How many Malignant Pleural Effusion clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (4 trials), Egypt (1 trial), China (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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