Registry for pleural fluid samples from lung cancer and infection patients
Official title: University of North Carolina Pleural Fluid Registry
Run by UNC Lineberger Comprehensive Cancer Center · NCT05620329 · Data updated 2026-11-12
This study is collecting fluid samples from patients with lung cancer or lung infections to see if they can help create better tests and treatments for these conditions.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 9999 (estimated) |
| Sponsor | UNC Lineberger Comprehensive Cancer Center Academic / other |
| Locations | 1 site (Chapel Hill, North Carolina) |
| Status | Recruiting |
| Started | January 24, 2018 |
| Main results expected | January 24, 2050 |
| Study ends | January 24, 2050 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT05620329 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have been diagnosed with pleural fluid and are undergoing clinically indicated drainage due to lung cancer or pulmonary infection.
✕Probably not a fit
Patients with concurrent medical conditions that may prevent safe pleural fluid drainage or incarcerated individuals may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to collect biospecimens, specifically pleural fluid, from patients diagnosed with lung cancer or pulmonary infections. By gathering these samples, researchers hope to gain insights into the underlying mechanisms of these conditions and develop new diagnostic tests and treatments. The registry will serve as a valuable resource for future research aimed at improving patient outcomes in lung-related diseases. Participants will include both inpatients and outpatients who meet specific clinical criteria.
Why it matters
Potential benefit: If successful, this study could lead to advancements in the understanding and treatment of lung cancer and related infections.
How similar studies have gone: While this approach is not widely tested, similar studies involving biospecimen collection have shown promise in advancing cancer research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who are 18 years or older * Inpatients and outpatients * Diagnosed with pleural fluid, are referred for and undergo clinically indicated drainage who have clinical evidence of: * pulmonary infection (such as fever, leukocytosis, new or worsening infiltrate on chest x-ray, or clinical deterioration) with effusion * malignancy Exclusion Criteria: * A subject will not be eligible for inclusion in this registry if, in the investigator's (or treating clinician's) opinion, the patient has any concurrent medical condition that may preclude their ability to undergo pleural fluid drainage safely. * Incarcerated individuals
Where it's running
-
UNC Lingeberger Comprehensive Cancer Center
Chapel Hill, North Carolina, United States Recruiting
Study contacts
- Principal investigator: Jason Akulian — UNC Lineberger Comprehensive Cancer Center
- Study coordinator: Carmmen Garcia
- Email: carmmene@med.unc.edu
- Phone: +1 954-336-7499
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.