Condition
Malignant Mesothelioma clinical trials and research
Research outlook What's coming for Mesothelioma: the next 6 months to 5 yearsAs of November 12, 2026, Find a Trial lists 4 Malignant Mesothelioma clinical trials that are recruiting, at sites in 2 countries (most in United States (4), China (1)). By phase: Phase 1 (2), Phase 1/2 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest Malignant Mesothelioma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Fast TIL therapy for cancers that have spread to the pleura, including mesothelioma | Phase 1 | Pittsburgh, Pennsylvania | Recruiting | Mar 2, 2026 |
| Fast TIL therapy for cancers that have spread to the pleura | Phase 1 | Pittsburgh, Pennsylvania | Recruiting | Sep 25, 2025 |
| Evaluating ISM6331 for advanced malignant mesothelioma and solid tumors | Phase 1/2 | Denver, Colorado and 9 other locations | Recruiting | Aug 22, 2024 |
| Additional chemotherapy after surgery for malignant peritoneal mesothelioma | Phase 2 | Chicago, Illinois and 12 other locations | Recruiting | Sep 28, 2023 |
All recruiting trials (4)
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Fast TIL therapy for cancers that have spread to the pleura, including mesothelioma
This study will try a patient's own pleural T cells grown briefly in the lab and given into the chest with local IL-2 to treat people with malignant pleural effusions or pleural mesothelioma who have exhausted standard treatments.
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Fast TIL therapy for cancers that have spread to the pleura
This treatment will try a patient's own pleural T cells, grown quickly in the lab and given into the chest with local IL-2, for adults whose cancer has spread to the pleura or for pleural mesothelioma.
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Evaluating ISM6331 for advanced malignant mesothelioma and solid tumors
This study is testing a new drug called ISM6331 to see if it is safe and effective for people with advanced malignant mesothelioma and other solid tumors who haven't had success with standard treatments.
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Additional chemotherapy after surgery for malignant peritoneal mesothelioma
This study is testing whether giving chemotherapy directly into the abdomen or through an IV after surgery helps people with malignant peritoneal mesothelioma do better.
Related topics
Quick answers
How many Malignant Mesothelioma clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (4 trials), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.