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Major Surgery clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Major Surgery clinical trials that are recruiting, at sites in 3 countries (most in Switzerland (2), France (1), Colombia (1)). By phase: Phase 4 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 3Countries
Newest Major Surgery clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Landiolol to prevent fast heart rates during major non-cardiac surgery in patients with cardiovascular risk | Phase 4 | Bern | Recruiting | Sep 11, 2025 |
| Comparing ketamine delivery methods for postoperative pain management in orthopedic surgery | Phase 4 | Medellín, Antioquia | Recruiting | Jan 14, 2025 |
| Evaluating the impact of standardized handover in major surgery | — | Boulogne-Billancourt | Recruiting | Jun 30, 2022 |
| Prehabilitation program for elderly patients undergoing major surgery | — | Bern, Canton of Bern | Recruiting | Jul 8, 2020 |
All recruiting trials (4)
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Landiolol to prevent fast heart rates during major non-cardiac surgery in patients with cardiovascular risk
This will test whether giving the ultra‑short acting beta‑blocker landiolol to people over 45 with cardiovascular risk factors who are having major non‑cardiac surgery can keep heart rate below 90 bpm throughout the perioperative period and reduce heart injury.
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Comparing ketamine delivery methods for postoperative pain management in orthopedic surgery
This study is testing whether giving ketamine through an IV or a patient-controlled pump works better for managing pain after major orthopedic surgery in adults.
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Evaluating the impact of standardized handover in major surgery
This study is testing if a new way for anesthetists to share important patient information during major surgery can help reduce serious problems after surgery and improve patient satisfaction.
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Prehabilitation program for elderly patients undergoing major surgery
This study tests if a special program that includes exercise, better nutrition, and other health improvements can help older patients recover better after major surgery compared to standard care.
Related topics
Quick answers
How many Major Surgery clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in Switzerland (2 trials), France (1 trial), Colombia (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.