Prehabilitation program for elderly patients undergoing major surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, randomized controlled trial aims to implement a multimodal, multidisciplinary prehabilitation approach to reduce postoperative complications and enhance recovery in elderly, frail patients scheduled for major surgery. The study involves two groups: one receiving standard care and the other participating in a prehabilitation program that includes exercise training, nutritional intervention, correction of anemia, and smoking cessation. By addressing various factors that affect surgical outcomes, the trial seeks to improve the overall health and recovery of elderly patients before undergoing surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Written informed consent
* comorbid (≥ASA 3)
* pre-existing fitness deficit: AT\<11ml/kg/min respectively VO2peak\<14ml/kg/min if AT unavailable or VE/VCO2 slope \> 33
* scheduled for major urologic, thoracic, visceral, orthopaedic or cardiovascular surgery
* screening at least 2 weeks prior to surgery

Exclusion Criteria:

* Paralysis or patients with mobility problems (who are unable to exercise),
* Premorbid conditions or orthopaedic impairments that contraindicate exercise,
* Cognitive disabilities,
* Chronic renal failure (need for dialysis)
* Emergency procedures.

Where it's running

• Department of Anaesthesiology and Pain Therapy, University Hospital Bern Inselspital Bern
  Bern, Canton of Bern, Switzerland Recruiting

Study contacts

• Principal investigator: Dominique A Engel, Dr — Department of Anaesthesiology and Pain Therapy, University Hospital Bern
• Study coordinator: Dominique A Engel, Dr
• Email: dominique.engel@insel.ch
• Phone: 0041316322111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.